Activity 14.7 Narcolepsy

This narcoleptic dachshund completely loses muscle tone without loss of consciousness when excited. Researchers at the Stanford University Center for Narcolepsy study narcolepsy both in humans and in animal models.

Textbook Reference: At Least Four Interacting Neural Systems Underlie Sleep pp. 433–438

Courtesy of Dr. Emmanuel Mignot and the Stanford University Center for Narcolepsy. For more information, see L. Lin et al., 1999. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 98(3):365–376.