Links for Keyword: Stroke

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Mini-strokes are thought to be fairly fleeting, often lasting a few minutes, but experiments conducted at a neuroscience lab in British Columbia paint a picture of a more lasting effect. Symptoms of mini-strokes are gone within 24 hours and no apparent lingering effects although they do heighten a person's risk of full-blown stroke in the future. They're transient, as one might infer from their formal name, transient ischemic attack. They've come and gone. Now researchers have used transcranial magnetic stimulation to examine patterns of brain activity in 13 patients who had experienced TIAs 14 to 30 days earlier, and compared them to the brain activity of 13 healthy people. Lara Boyd, a neuroscientist with the Brain Research Centre at Vancouver Coastal Health Research Institute and the University of British Columbia, said magnetic resonance imaging might or might not reveal a little damaged area or lesion in the brain after a TIA. "But we wondered if we could maybe detect something with neurophysiology, with electro-physiology, that has previously gone unnoticed," she said in an interview. The non-invasive method involves putting a pulse of electrical current into the brain; for example, it allows scientists to measure how much current is needed to cause a motor response, such as a muscle twitch. © CBC 2011

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14928 - Posted: 01.29.2011

Cooling the brain of patients who have suffered a stroke could dramatically improve their recovery, a group of Scottish doctors has said. They are joining others from across Europe who believe that inducing hypothermia in some patients can boost survival rates and reduce brain damage. Similar techniques have already been tried successfully on heart attack patients and those with birth injuries. Scientists are in Brussels to discuss a Europe-wide trial of the technique. To date, studies have involved the body of patients being cooled using ice cold intravenous drips and cooling pads applied to the skin. This lowers the body temperature to about 35C, just a couple of degrees below its normal level. The technique puts the body into a state of artificial hibernation, where the brain can survive with less blood supply, giving doctors vital time to treat blocked or burst blood vessels. Dr Malcolm Macleod, head of experimental neuroscience at the Centre for Clinical Brain Sciences at the University of Edinburgh, said: "Every day 1,000 Europeans die from stroke - that's one every 90 seconds - and about twice that number survive but are disabled. BBC © MMXI

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14910 - Posted: 01.24.2011

Giving stroke patients Prozac soon after the event could help their recovery from paralysis, a study has found. Researchers discovered more improvement in movement and greater independence after three months in patients taking the antidepressant (also known as fluoxetine), compared to placebo. The Lancet Neurology study was based on research on 118 patients in France. UK stroke experts said the findings were "promising". This was the largest study of selective serotonin re-uptake inhibitors (SSRIs) and stroke recovery to date. Tests on stroke patients 90 days after being given the drug found that patients taking fluoxetine had gained significantly more function in their upper and lower limbs than patients who were not given the drug. Patients in the fluoxetine group were also more likely to be coping independently. All patients in the study had moderate to severe motor disabilities following their stroke. The study noted that the side-effects from the antidepressant were generally mild and infrequent, although this group did notice more instances of nausea and diarrhoea. BBC © MMXI

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry; Chapter 16: Psychopathology: Biological Basis of Behavior Disorders
Related chapters from MM:Chapter 15: Language and Our Divided Brain; Chapter 12: Psychopathology: Biological Basis of Behavioral Disorders
Link ID: 14850 - Posted: 01.10.2011

By Rachael Rettner Too much fried fish may contribute to the high rate of stroke in America's "stroke belt," according to a new study. The results showed that people living in the stroke belt — including residents of North Carolina, South Carolina, Georgia, Alabama, Mississippi, Tennessee, Arkansas and Louisiana — were about 30 percent more likely to eat two or more servings of fried fish every week than those living in the rest of the country, the researchers said. And blacks who are known to have an increased risk of stroke regardless of where they live, were more than 3.5 times more likely to eat two or more servings of fried fish per week than whites. Inhabitants of the stroke belt are 20 percent more likely to die from stroke than those living in the rest of the country. And those in the stroke "buckle" — an area of the stroke belt that includes the coastal plains of North Carolina, South Carolina and Georgia — are 40 percent more likely to die from stroke, said study researcher Fadi Nahab of Emory University in Atlanta. Fried fish, Nahab said, may be contributing to these racial and geographic disparities. MyHealthNewsDaily Copyright © 2010.

Related chapters from BP7e: Chapter 13: Homeostasis: Active Regulation of the Internal Environment; Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 9: Homeostasis: Active Regulation of the Internal Environment; Chapter 15: Language and Our Divided Brain
Link ID: 14821 - Posted: 12.27.2010

By Garrison Keillor People keep asking about my stroke. I am okay, really--not staggering around with one arm hanging limp, or glassy-eyed or slurring my speech, flecks of spittle on my lips. And yet people still say, "How are you doing?" in that special way that means, "Tell us the painful truth and feel free to cry." Really, it was only a minor stroke, but I will tell about it one last time and then let's move on to something interesting--such as sex or sweet corn or the Rapture--and I will never discuss this again. Thank you for your patience. It happened on Labor Day, 2009, in Minneapolis, at a massage studio (the kind with the Japanese prints and the Peruvian flute music and the careful placement of the towel of modesty). I lay on my belly under the hands of the powerful Jamaican masseuse, Angelica, who was working on my neck and shoulders and telling me how good her life had been since she turned it over to the Lord Jesus Christ and let Him make all the decisions. "Including what to eat?" I asked. Yes, she said. I started to say something witty about honey and locusts and whoa my mouth was numb, my speech slurred. My brain was melting. I heisted up on my elbows. I took a deep breath. She said, "Are you okay?" I said (as I was brought up to say), "I am just fine." ©2010 Rodale Inc.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14777 - Posted: 12.14.2010

By Laura Sanders SAN DIEGO — In the two-hour window after a stroke, flicking a single whisker completely prevents many damaging effects in a rat, a new study finds. The cheap, simple intervention, described November 15 at a news conference at the annual Society for Neuroscience meeting, may represent a new way to minimize disability after a stroke. “I think it’s one of the most profound findings that have come along in recent years,” said neuroscientist Carol Barnes of the University of Arizona in Tucson. “There is no brain damage. It’s almost a miracle. It’s almost too good to be true. Any protection would be good, but this is more than dramatic.” Researchers led by Ron Frostig of the University of California, Irvine mimicked a stroke by severing a major blood vessel in rats’ brains. Then at times during the two hours immediately afterward, a mechanical rod stimulated a single whisker on the anesthetized rat for a total of less than five minutes. With whisker stimulation, the team saw that blood began to flow backward through the severed vessel and got rerouted through other vessels, ultimately reaching the brain area that would have been deprived of blood. No such rerouting was present in rats that didn’t have a whisker stimulated, or in rats that had whisker stimulation more than two hours after the stroke. The team’s preliminary data suggest that the method works for conscious rats, too. © Society for Science & the Public 2000 - 2010

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14686 - Posted: 11.17.2010

Helen Thomson, biomedical news editor, San Diego This weekend I was shown how a virtual reality piano has helped people who have had a stroke regain movement in their limbs. This game, and others like it, aid the functional reorganisation of the brain and could pave the way for faster improvements in stroke therapy. Soha Saleh, at the New Jersey Institute of Techonology, and colleagues used a robotic glove, together with various video games, to train four volunteers who had suffered stroke and lost near-total movement of their upper limbs. The four subjects were trained for 3 hours a day over 8 days. Each training session involved making finger and hand movements with the aid of a robotic glove which gave a small amount of support to volunteers' mobility, such as holding groups of fingers together so that the volunteer could concentrate on moving just one. The volunteers were instructed on what movements to perform by playing computer games involving stacking items on a shelf or playing tunes on a piano. Their movements were transmitted into the video game to provide immediate visual feedback. The subjects were tested for breadth of movement and questioned on their ability to perform everyday tasks before and after the training sessions. All four participants showed improvements in movement after the task, with an average improvement of 24 per cent in tasks such as reaching for ones nose. © Copyright Reed Business Information Ltd.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14677 - Posted: 11.16.2010

Taking vitamin E could slightly increase the risk of a particular type of stroke, a study says. The British Medical Journal study found that for every 1,250 people there is the chance of one extra haemorrhagic stroke - bleeding in the brain. Researchers from France, Germany and the US studied nine previous trials and nearly 119,000 people. But the level at which vitamin E becomes harmful is still unknown, experts say. The study was carried out at Harvard Medical School, Boston, and INSERM in Paris. Haemorrhagic strokes are the least common type and occur when a weakened blood vessel supplying the brain ruptures and causes brain damage. Researchers found that vitamin E increased the risk of this kind of stroke by 22%. The study also found that vitamin E could actually cut the risk of ischaemic strokes - the most common type of stroke - by 10%. Ischaemic strokes account for 70% of all cases and happen when a blood clot prevents blood reaching the brain. Experts found vitamin E could cut the risk, equivalent to one ischaemic stroke prevented per 476 people taking the vitamin. BBC © MMX

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14632 - Posted: 11.06.2010

by Karen Heyman One-third of stroke survivors never recover enough brain function to live on their own. Now scientists think they know why. Once a stroke kills a swath of brain cells, a neurotransmitter known as GABA impairs the surviving, apparently healthy, brain tissue. Targeting GABA could help a stroke-afflicted brain better overcome its damage, the researchers suggest. When a stroke hits, physicians have few options. If they catch it early enough, they can administer the clot-busting drug tPA to keep even more brain cells from dying—but tPA is not appropriate for all types of stroke. Physicians can also prescribe physical therapy, which can occasionally help recover impaired motor function. Yet there are no approved drugs that help the brain heal. For its part, the brain appears to try a sort of natural drug therapy to limit the spread of damage. It releases extra amounts of GABA, which reduces the firing of neurons. GABA initially prevents stroke-damaged brain tissue from becoming overexcited and dying. But University of California, Los Angeles (UCLA), investigators led by Thomas Carmichael, a specialist in stroke, and Istvan Mody, an expert in inhibition, wondered whether GABA might also interfere with the brain's plasticity, the ability of healthy regions to take over for injured ones. Previous studies had tried to address this question, but they produced confusing results. The UCLA team hypothesized that others had failed to distinguish between two types of inhibition—phasic, in which GABA acts upon specific receptors at nerve cell sites called synapses, and tonic, in which the neurotransmitter acts on other receptors elsewhere on the nerve cell. © 2010 American Association for the Advancement of Science.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Related chapters from MM:Chapter 15: Language and Our Divided Brain; Chapter 2: Cells and Structures: The Anatomy of the Nervous System
Link ID: 14626 - Posted: 11.04.2010

By Nathan Seppa MRI scans of stroke patients can indicate when the stroke occurred, a revelation that could allow more aggressive treatment to limit brain damage, French researchers report online November 2 in Radiology. For a person arriving at a hospital with a stroke, the clock is ticking. When a clot obstructs an artery in the brain, millions of neurons are lost with each passing minute as tissue is starved of blood and oxygen. A clot-busting drug called tPA, or tissue plasminogen activator, can often dissolve the clot and free up the vessel. But the drug is generally considered safe to administer only in the first three to 4½ hours after a stroke begins (SN: 10/25/08, p. 16). Stoke patients typically get a CT scan, which enables doctors to discern whether the stroke results from a blood clot or, less commonly, from a hemorrhage, which shows up as a dark mass on the CT, says neurologist Andrew Barreto of the University of Texas Medical School at Houston. MRI, or magnetic resonance imaging, is used much less often and usually only at large medical centers. Unfortunately, a CT scan cannot pinpoint when a stroke began. Neither can many patients, either because they can’t recall exactly when their symptoms first appeared or because they woke up already in the throes of a stroke. In such cases, doctors “guesstimate” the stroke’s onset, Barreto says, but hesitate to give tPA if too many hours might have passed. Giving tPA too late won’t help tissue that’s already dead and risks causing a brain bleed. After the tPA window closes there is little doctors can do but monitor the patient. © Society for Science & the Public 2000 - 2010

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Related chapters from MM:Chapter 15: Language and Our Divided Brain; Chapter 2: Cells and Structures: The Anatomy of the Nervous System
Link ID: 14625 - Posted: 11.04.2010

Nicole Baute Living Reporter Stroke victims are 12 per cent more likely to die within seven days if they arrive at the hospital on the weekend, according to a study of more than 20,000 Ontario patients. The study, published today in Neurology, found that patients received the same major interventions — brain scans, clot-busting medications and admission to stroke units — regardless of when they were admitted. Dr. Moira Kapral, a researcher at the Institute for Clinical Evaluative Sciences and one of the study’s authors, says it is possible that the weekend effect is caused by “an accumulation of small deficiencies in care” — including secondary treatment that is nonetheless crucial for recovery. For example, she says, there might be fewer or less-experienced staff working on the weekends. Or patients might experience delays in access to rehabilitation experts, such as physiotherapists who help stroke patients regain mobility or speech pathologists who do swallowing assessments to determine whether or not it’s safe to eat. Further research is necessary to examine these possibilities. In the meantime, says Kapral, health-care administrators should try to determine what is causing the increased mortality gap. “I think hospitals should really look at their weekend practices in terms of staffing and resources to see if there are things that can be done to improve care on weekends.” © Copyright Toronto Star 1996-2010

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14620 - Posted: 11.04.2010

A new stroke prevention clinic in Ottawa is helping patients treated for mini-strokes from developing the full-blown version, doctors report. A transient ischemic attack, or TIA, is a mild stroke that causes stroke symptoms such as sudden numbness of the face, arm or leg. The symptoms last for less than 24 hours and then resolve on their own without disabling neurological effects, but it is a marker for early risk of stroke. At the Ottawa Hospital Stroke Clinic, patients with TIA symptoms are quickly assessed in the emergency department (ED) and referred to the stroke clinic for brain imaging, medication adjustment, counselling about stroke risk factors and surgery in some cases. Dr. Mukul Sharma, deputy director of the Canadian Stroke Network, and his co-authors found that 3.2 per cent of people who experienced TIA at the stroke prevention clinic developed a full-blown stroke within 90 days, compared with about 10 per cent at other centres. "The beauty of this is that we added very few staff," said Sharma, lead author of the study in the November issue of the journal Stroke, and director of The Ottawa Hospital Stroke Clinic. A booking clerk was one of the few staff that was added as part of the program. "It really is that ability to juggle bookings and the acuity of the visit that I think make this process work. I've likened it to getting an orchestra playing the same tune." © CBC 2010

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14608 - Posted: 10.30.2010

Lauran Neergaard, Associated Press - When her stroke hit, Edna Wooten somehow stopped her car. Then her daughter ignored her slurred protests and raced her to the hospital - in time for a drug to dissolve the blood clot causing her stroke. Wooten was lucky: Too few stroke sufferers get that clot-busting treatment, especially black and Latino patients who are at highest risk of having a stroke and also may be hesitant to seek fast care. New research is targeting those underserved populations to better spread the word that "time is brain" - the faster you move, the more brain you save. "We basically scare people so much about stroke, it motivates them to denial," says Dr. Lewis Morgenstern of the University of Michigan, an expert on stroke disparities. "What we haven't done a good job of is telling people there is an effective treatment, that people are in control of their own destiny." That was the message that stroke educator Shauna St. Clair of Georgetown University took to a senior center in a predominantly black neighborhood in Washington last week, part of a project funded by the National Institutes of Health. "Damaged brain cells we can fix. That's why we want you to get treatment as soon as possible," St. Clair told the rapt group. "If they stay damaged, they die." © 2010 Hearst Communications Inc.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14555 - Posted: 10.14.2010

By Nathan Seppa The dismal range of options for treating a stroke might be improving. Scientists report that neutralizing an enzyme called NOX4 that shows up in stroke-damaged tissues can limit brain injury in mice. The study appears in the September PLoS Biology. Stroke treatment is often hampered because the primary available drug, a clot-buster called tPA, is effective only within three hours of a stroke’s onset; many strokes are not detected until after that window has closed. Knowing the molecular culprits involved in brain tissue damage caused by a stroke might give scientists another angle to exploit as they seek treatments, says Harald Schmidt, a physician and pharmacologist at Maastricht University in the Netherlands. To that end, Schmidt teamed with an international group of scientists to study the role of NOX4, a member of an enzyme family that makes free radicals — highly reactive molecules that can kill cells and contribute to tissue damage. The researchers induced strokes in mice by threading a filament up an artery into the brain to a point at which it obstructed the vessel. In a series of experiments, the scientists found that mice genetically engineered to lack the NOX4 enzyme showed substantially less damage from these strokes than mice making NOX4. In other tests, normal mice with the ability make the NOX enzymes fared better against strokes when given an experimental drug that neutralized NOX4 than did mice not receiving the drug. © Society for Science & the Public 2000 - 2010

Related chapters from BP7e: Chapter 1: Biological Psychology: Scope and Outlook; Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 1: An Introduction to Brain and Behavior; Chapter 15: Language and Our Divided Brain
Link ID: 14483 - Posted: 09.23.2010

By Carolyn Y. Johnson In the ever-expanding world of medical devices, early adopters have a new option: a robotic arm. A Cambridge start-up, Myomo Inc., is making an expensive stroke therapy available directly to patients, an effort to encourage use of the novel device. The Myomo arm, based on technology developed at the Massachusetts Institute of Technology, is in many ways a natural extension of research that has shown repetitive-exercise therapy can help stroke patients regain movement. The lightweight prosthesis straps onto the arm and reads signals from the muscles to give a patient an assist when he or she moves the limb. But there is no rigorous scientific evidence demonstrating how well it works. And the $7,000 device casts a spotlight on the hard-to-navigate world of rehabilitation devices — in which patients who are often desperate face a growing number of products whose effectiveness is still being determined. “While there’s some suggestive, tiny studies — that are really pilot studies — that it might be useful, there’s no proof of efficacy using the usual criteria,’’ said Dr. Joel Stein, chairman of the rehabilitation and regenerative medicine department at Columbia University. He is also on Myomo’s scientific advisory board. “I’ve worked with many stroke patients through the years, and I’m careful to not be too paternalistic deciding for them. . . . They feel like the medical system has given up on them, and there’s a fine line between not over-promising and saying we have nothing shown to be helpful, therefore you should just give up.’’ © 2010 NY Times Co

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry; Chapter 11: Motor Control and Plasticity
Related chapters from MM:Chapter 15: Language and Our Divided Brain; Chapter 5: The Sensorimotor System
Link ID: 14337 - Posted: 08.09.2010

by Linda Geddes, Amsterdam THE discovery of an antibody that binds to certain brain receptors could reduce the side effects of a common stroke drug and buy additional time in which to use it. The preferred treatment for ischaemic stroke, in which a blood clot cuts off the blood supply to brain tissue, is a drug called rtPA, which dissolves the clot. However, that drug has to be given within the first few of hours of a stroke, otherwise the risks of treatment outweigh the benefits. Dissolving the clot can lead to a sudden rise in blood pressure, increasing the chance that a blood vessel will rupture and bleed into the brain. Only 5 to 10 per cent of people who suffer a stroke make it to hospital early enough to be treated with rtPA, says Denis Vivien of the University of Caen Basse-Normandie in France. The rest are given drugs that do not destroy the initial clot but reduce the chance of further clots forming. One reason for a delay in administering rtPA is that a brain scan must be carried out to determine the nature of the stroke. People with haemorrhagic stroke, in which a blood vessel in the brain bursts, should not receive rtPA as it increases the risk of bleeding. Now a startling discovery by Vivien has put a different perspective on this relatively simple picture: rtPA is actually released by brain cells. "This was completely unexpected," he says. © Copyright Reed Business Information Ltd.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 14243 - Posted: 07.10.2010

By JONATHAN DIENST My son Jared lay in a bed at NewYork-Presbyterian/Weill Cornell hospital, limp and pale, his 7-year-old body tethered to a tangle of tubes and monitor wires. A neurologist, Dr. Maurine Packard, stood to his left. “Jared,” I recall her saying. “Pay attention to what I say.” And then, in a strong, firm voice: “The barn is red.” She waited a few moments and asked, “What color is the barn?” Jared started to answer, then froze. My wife and I, sitting behind Dr. Packard, froze too. Two days before, he had been a happy, athletic second grader, a beautiful boy who loved playing baseball and basketball in the park. Now he couldn’t walk; he had to struggle to remember the color of a barn. He tried again, and then replied in a weak, slurred voice. “No,” Jared said. Dr. Packard nodded, as if that was the answer she had expected. Before June 23, 2008, my wife, Victoria, and I had never heard of a child’s having a stroke. Most people, many doctors included, still haven’t. In the agonizing months that followed, we heard it over and over: “But children don’t have strokes.” How little we knew. It turns out that stroke, by some estimates, is the sixth leading cause of death in infants and children. And experts say doctors and hospitals need to be far more aggressive in detecting and treating it. Copyright 2010 The New York Times Company

Related chapters from BP7e: Chapter 7: Life-Span Development of the Brain and Behavior; Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 13: Memory, Learning, and Development; Chapter 15: Language and Our Divided Brain
Link ID: 13689 - Posted: 06.24.2010

By RONI CARYN RABIN Residents of the Southeast are so much more likely than other Americans to die of a stroke that epidemiologists call the region the “stroke belt.” A new study suggests that the risk may be established early in life, because even when those born in the South relocate to another region as adults, they carry the increased risk of stroke with them. Harvard School of Public Health researchers who analyzed stroke deaths across the United States found that people who were born in the Southeast and continued to live there as adults were 34 percent more likely than other Americans to die of a stroke in the year 2000. But even those who moved away faced an increased risk, with whites 20 percent more likely and blacks 9 percent more likely to die of a stroke than Americans who lived their entire lives outside the region, the study found. The stroke belt includes Alabama, Arkansas, Georgia, Mississippi, North Carolina, South Carolina and Tennessee. The study, published in the Dec. 1 issue of the journal Neurology, analyzed death rates from 1980, 1990 and 2000. Though stroke death rates declined over time, the study found consistent patterns of elevated risk through the decades. Copyright 2009 The New York Times Company

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry; Chapter 7: Life-Span Development of the Brain and Behavior
Related chapters from MM:Chapter 15: Language and Our Divided Brain; Chapter 13: Memory, Learning, and Development
Link ID: 13530 - Posted: 06.24.2010

Vitamin E supplements do not protect healthy women against heart attacks and stroke, according to new results from the Women’s Health Study, a long-term clinical trial of the effect of vitamin E and aspirin on both the prevention of cardiovascular disease and of cancer. The vitamin E results of the Women’s Health Study are published in the July 6 issue of the Journal of the American Medical Association. In addition to the cardiovascular disease findings, the study authors report that there was no effect of vitamin E on total cancer or on the most common cancers in women — breast, lung, and colon cancers. The Women’s Health Study was funded by the National Heart, Lung, and Blood Institute (NHLBI) and the National Cancer Institute of the National Institutes of Health. “This landmark trial has given women and their physicians important health information. We can now say that despite their initial promise, vitamin E supplements do not prevent heart attack and stroke. Instead, women should focus on well proven means of heart disease prevention, including leading a healthy lifestyle and controlling risk factors such as high blood pressure and high cholesterol,” said NHLBI Director Elizabeth G. Nabel, M.D. The Women’s Health Study was conducted between 1992 and 2004. The participants were 39,876 healthy women age 45 years and older who were randomly assigned to receive 600 IU of Vitamin E or placebo and low-dose aspirin or placebo on alternate days. The participants were followed for an average of 10.1 years. The aspirin results published last March found no benefit of aspirin (100 mg every other day) in preventing first heart attacks or death from cardiovascular causes in women but did find a reduced risk of stroke overall, as well as reduced risk of both stroke and heart attack in women aged 65 and older.

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 7597 - Posted: 06.24.2010

ST. PAUL, MN - Public education is needed about the symptoms and risks of mini-stroke, also called transient ischemic attack or TIA, according to the first large study on the topic, which is published in the May 13 issue of Neurology, the scientific journal of the American Academy of Neurology. The study found that only 9 percent of people could give the definition of a TIA or identify a symptom of TIA. TIA symptoms are the same as those for a regular stroke, but TIA symptoms resolve themselves within 24 hours. The phone survey of more than 10,000 people found that 3.2 percent had TIA symptoms but never saw a physician about them. Among those with a TIA diagnosis, 16 percent saw the doctor more than a week after the symptoms occurred. “People think that because these symptoms go away quickly, they don’t need to worry about them, but that’s definitely not the case,” said study author and neurologist S. Claiborne Johnston, MD, PhD, of the University of California, San Francisco. “People who’ve had a TIA are at high risk of having a stroke, particularly in the first few days after the TIA, and doctors can help them reduce that risk. ”

Related chapters from BP7e: Chapter 19: Language and Hemispheric Asymmetry
Related chapters from MM:Chapter 15: Language and Our Divided Brain
Link ID: 3830 - Posted: 06.24.2010