Chapter 14. Attention and Consciousness
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by Helen Thomson We meet in a pub, we have a few drinks, some dinner and then you lean in for a kiss. You predict, based on our previous interactions, that the kiss will be reciprocated – rather than landing you with a slap in the face. All our social interactions require us to anticipate another person's undecided intentions and actions. Now, researchers have discovered specific brain cells that allow monkeys to do this. It is likely that the cells do the same job in humans. Keren Haroush and Ziv Williams at Harvard Medical School trained monkeys to play a version of the prisoner's dilemma, a game used to study cooperation. The monkeys sat next to each other and decided whether or not they wanted to cooperate with their companion, by moving a joystick to pick either option. Moving the joystick towards an orange circle meant cooperate, a blue triangle meant "not this time". Neither monkey could see the other's face, or receive any clues about their planned action. If the monkeys cooperated, both received four drops of juice. If one cooperated and the other decided not to, the one who cooperated received one drop, and the other received six drops of juice. If both declined to work together they both received two drops of juice. Once both had made their selections, they could see what the other monkey had chosen and hear the amount of juice their companion was enjoying. © Copyright Reed Business Information Ltd.
Link ID: 20627 - Posted: 02.27.2015
Elizabeth Gibney DeepMind, the Google-owned artificial-intelligence company, has revealed how it created a single computer algorithm that can learn how to play 49 different arcade games, including the 1970s classics Pong and Space Invaders. In more than half of those games, the computer became skilled enough to beat a professional human player. The algorithm — which has generated a buzz since publication of a preliminary version in 2013 (V. Mnih et al. Preprint at http://arxiv.org/abs/1312.5602; 2013) — is the first artificial-intelligence (AI) system that can learn a variety of tasks from scratch given only the same, minimal starting information. “The fact that you have one system that can learn several games, without any tweaking from game to game, is surprising and pretty impressive,” says Nathan Sprague, a machine-learning scientist at James Madison University in Harrisonburg, Virginia. DeepMind, which is based in London, says that the brain-inspired system could also provide insights into human intelligence. “Neuroscientists are studying intelligence and decision-making, and here’s a very clean test bed for those ideas,” says Demis Hassabis, co-founder of DeepMind. He and his colleagues describe the gaming algorithm in a paper published this week (V. Mnih et al. Nature 518, 529–533; 2015. Games are to AI researchers what fruit flies are to biology — a stripped-back system in which to test theories, says Richard Sutton, a computer scientist who studies reinforcement learning at the University of Alberta in Edmonton, Canada. “Understanding the mind is an incredibly difficult problem, but games allow you to break it down into parts that you can study,” he says. But so far, most human-beating computers — such as IBM’s Deep Blue, which beat chess world champion Garry Kasparov in 1997, and the recently unveiled algorithm that plays Texas Hold ’Em poker essentially perfectly (see Nature http://doi.org/2dw; 2015)—excel at only one game. © 2015 Nature Publishing Group
People with attention deficit hyperactivity disorder are about twice as likely to die prematurely as those without the disorder, say researchers. Researchers followed 1.92 million Danes, including 32,000 with ADHD, from birth through to 2013. "In this nationwide prospective cohort study with up to 32-year followup, children, adolescents and adults with ADHD had decreased life expectancy and more than double the risk of death compared with people without ADHD," Soren Dalsgaard, from Aarhus University in Denmark, and his co-authors concluded in Wednesday's online issue of Lancet. Actress Kirstie Alley holds a picture of Raymond Perone while testifying in favour of a bill designed to curb the over-prescribing of psychotropic drugs. Danish researchers studying ADHD say medications can reduce symptoms of inattention and impulsivity. (Phil Coale/Associated Press) "People diagnosed with ADHD in adulthood had a greater risk of death than did those diagnosed in childhood and adolescence. This finding could be caused by persistent ADHD being a more severe form of the disorder." Of the 107 individuals with ADHD who died, information on cause of death was available for 79. Of those, 25 died from natural causes and 54 from unnatural causes, including 42 from accidents. Being diagnosed with ADHD along with oppositional defiant disorder, conduct disorder and substance use disorder also increased the risk of death, the researchers found. Mortality risk was also higher for females than males, which led Dalsgaard to stress the need for early diagnosis, especially in girls and women, and to treat co-existing disorders. Although talk of premature death will worry parents and patients, they can seek solace in knowing the absolute risk of premature death at an individual level is low and can be greatly reduced with treatment, Stephen Faraone, a professor of psychiatry and director of child and adolescent psychiatry research at SUNY Upstate Medical University in New York, said in a journal commentary published with the study. ©2015 CBC/Radio-Canada.
|By Matthew Hutson We like to think of our moral judgments as consistent, but they can be as capricious as moods. Research reveals that such judgments are swayed by incidental emotions and perceptions—for instance, people become more moralistic when they feel dirty or sense contamination, such as in the presence of moldy food. Now a series of studies shows that hippies, the obese and “trailer trash” suffer prejudicial treatment because they tend to elicit disgust. Researchers asked volunteers to read short paragraphs about people committing what many consider to be impure acts, such as watching pornography, swearing or being messy. Some of the paragraphs described the individuals as being a hippie, obese or trailer trash—and the volunteers judged these fictional sinners more harshly, according to the paper in the Journal of Experimental Psychology: General. Questionnaires revealed that feelings of disgust toward these groups were driving the volunteers' assessments. A series of follow-up studies solidified the link, finding that these groups also garnered greater praise for purity-related virtues, such as keeping a neat cubicle. If the transgression in question did not involve purity, such as not tipping a waiter, the difference in judgment disappeared. “The assumption people have is that we draw on values that are universal and important,” says social psychologist E. J. Masicampo of Wake Forest University, who led the study, “but something like mentioning that a person is overweight can really push that judgment around. It's triggering these gut-level emotions.” The researchers also looked for real-world effects. © 2015 Scientific American
By Christie Aschwanden Paul Offit likes to tell a story about how his wife, pediatrician Bonnie Offit, was about to give a child a vaccination when the kid was struck by a seizure. Had she given the injection a minute sooner, Paul Offit says, it would surely have appeared as though the vaccine had caused the seizure and probably no study in the world would have convinced the parent otherwise. (The Offits have such studies at the ready — Paul is the director of the Vaccine Education Center at the Children’s Hospital of Philadelphia and author of “Deadly Choices: How the Anti-Vaccine Movement Threatens Us All.”) Indeed, famous anti-vaxxer Jenny McCarthy has said her son’s autism and seizures are linked to “so many shots” because vaccinations preceded his symptoms. But, as Offit’s story suggests, the fact that a child became sick after a vaccine is not strong evidence that the immunization was to blame. Psychologists have a name for the cognitive bias that makes us prone to assigning a causal relationship to two events simply because they happened one after the other: the “illusion of causality.” A study recently published in the British Journal of Psychology investigates how this illusion influences the way we process new information. Its finding: Causal illusions don’t just cement erroneous ideas in the mind; they can also prevent new information from correcting them. Helena Matute, a psychologist at Deusto University in Bilbao, Spain, and her colleagues enlisted 147 college students to take part in a computer-based task in which they each played a doctor who specializes in a fictitious rare disease and assessed whether new medications could cure it. ©2015 ESPN Internet Ventures.
Tom Stafford Trusting your instincts may help you to make better decisions than thinking hard, a study suggests. It is a common misconception that we know our own minds. As I move around the world, walking and talking, I experience myself thinking thoughts. "What shall I have for lunch?", I ask myself. Or I think, "I wonder why she did that?" and try and figure it out. It is natural to assume that this experience of myself is a complete report of my mind. It is natural, but wrong. There's an under-mind, all psychologists agree – an unconscious which does a lot of the heavy lifting in the process of thinking. If I ask myself what is the capital of France the answer just comes to mind – Paris! If I decide to wiggle my fingers, they move back and forth in a complex pattern that I didn't consciously prepare, but which was delivered for my use by the unconscious. The big debate in psychology is exactly what is done by the unconscious, and what requires conscious thought. Or to use the title of a notable paper on the topic, 'Is the unconscious smart or dumb?' One popular view is that the unconscious can prepare simple stimulus-response actions, deliver basic facts, recognise objects and carry out practised movements. Complex cognition involving planning, logical reasoning and combining ideas, on the other hand, requires conscious thought. A recent experiment by a team from Israel scores points against this position. Ran Hassin and colleagues used a neat visual trick called Continuous Flash Suppression to put information into participants’ minds without them becoming consciously aware of it.
Link ID: 20594 - Posted: 02.19.2015
Carl Zimmer In 2010, a graduate student named Tamar Gefen got to know a remarkable group of older people. They had volunteered for a study of memory at the Feinberg School of Medicine at Northwestern University. Although they were all over age 80, Ms. Gefen and her colleagues found that they scored as well on memory tests as people in their 50s. Some complained that they remembered too much. She and her colleagues referred to them as SuperAgers. Many were also friends. “A couple tried to set me up with their grandsons,” Ms. Gefen said. She was impressed by their resilience and humor: “It takes wisdom to a whole new level.” Recently, Ms. Gefen’s research has taken a sharp turn. At the outset of the study, the volunteers agreed to donate their brains for medical research. Some of them have died, and it has been Ms. Gefen’s job to look for anatomical clues to their extraordinary minds. “I had this enormous privilege I can’t even begin to describe,” she said. “I knew them and tested them in life and in death. At the end, I was the one looking at them through a microscope.” Ms. Gefen and her colleagues are now starting to publish the results of these post-mortem studies. Last month in The Journal of Neuroscience, the scientists reported that one of the biggest differences involves peculiar, oversize brain cells known as von Economo neurons. SuperAgers have almost five times as many of them as other people. Learning what makes these brains special could help point researchers to treatments for Alzheimer’s disease and other kinds of mental decline. But it is hard to say how an abundance of von Economo neurons actually helps the brain. © 2015 The New York Times Company
By Virginia Morell To prevent their hives from being attacked by invaders, wasps must quickly distinguish friend from foe. They typically do this by sniffing out foreigners, as outsiders tend to have a different scent than the home colony. Now researchers have discovered that, like a few other wasp species, a tiny social wasp (Liostenogaster flavolineata) from Malaysia employs an additional security measure: facial recognition. The wasps’ nests are typically found in large aggregations with as many as 150 built close together, and each colony faces persistent landing attempts by outsiders from these other nests. To find out why and how these wasps employ both vision and scent to determine if an incoming wasp is a comrade, scientists carried out a series of experiments on 50 colonies (see photo above) in the wild. Close to the nests, the researchers dangled lures made of captured and killed wasps. The lures had been given different treatments. For instance, some lures made from nest mates were coated with a foe’s scent, whereas outsiders were painted with the colony’s odor. The wasps, it turns out, pay more attention to facial markings than to scent when faced with a possible intruder, the team reports online today in the Proceedings of the Royal Society B. Indeed, in tests where the wasps could assess both an intruder’s face and scent, they relied solely on facial recognition and immediately attacked those whose faces they didn’t know, ignoring their odor. That’s the safest strategy, the scientists note, because the wasps can recognize another’s face at a distance, but need to actually touch another wasp to detect her scent—not a bad ploy for a tiny-brained insect. © 2015 American Association for the Advancement of Science
Link ID: 20547 - Posted: 02.05.2015
By Katherine Ellison Dr. Mark Bertin is no A.D.H.D. pill-pusher. The Pleasantville, N.Y., developmental pediatrician won’t allow drug marketers in his office, and says he doesn’t always prescribe medication for children diagnosed with attention deficit hyperactivity disorder. Yet Dr. Bertin has recently changed the way he talks about medication, offering parents a powerful argument. Recent research, he says, suggests the pills may “normalize” the child’s brain over time, rewiring neural connections so that a child would feel more focused and in control, long after the last pill was taken. “There might be quite a profound neurological benefit,” he said in an interview. A growing number of doctors who treat the estimated 6.4 million American children diagnosed with A.D.H.D. are hearing that stimulant medications not only help treat the disorder but may actually be good for their patients’ brains. In an interview last spring with Psych Congress Network, http://www.psychcongress.com/video/are-A.D.H.D.-medications-neurotoxic-or-neuroprotective-16223an Internet news site for mental health professionals, Dr. Timothy Wilens, chief of child and adolescent psychiatry at Massachusetts General Hospital, said “we have enough data to say they’re actually neuroprotective.” The pills, he said, help “normalize” the function and structure of brains in children with A.D.H.D., so that, “over years, they turn out to look more like non-A.D.H.D. kids.” Medication is already by far the most common treatment for A.D.H.D., with roughly 4 million American children taking the pills — mostly stimulants, such as amphetamines and methylphenidate. Yet the decision can be anguishing for parents who worry about both short-term and long-term side effects. If the pills can truly produce long-lasting benefits, more parents might be encouraged to start their children on these medications early and continue them for longer. Leading A.D.H.D. experts, however, warn the jury is still out. © 2015 The New York Times Company
|By Esther Landhuis One in nine Americans aged 65 and older has Alzheimer's disease, a fatal brain disorder with no cure or effective treatment. Therapy could come in the form of new drugs, but some experts suspect drug trials have failed so far because compounds were tested too late in the disease's progression. By the time people show signs of dementia, their brains have lost neurons. No therapy can revive dead cells, and little can be done to create new ones. So researchers running trials now seek participants who still pass as cognitively normal but are on the verge of decline. These “preclinical” Alzheimer's patients may represent a window of opportunity for therapeutic intervention. How to identify such individuals before they have symptoms presents a challenge, however. Today most Alzheimer's patients are diagnosed after a detailed medical workup and extensive tests that gauge mental function. Other tests, such as spinal fluid analyses and positron-emission tomography (PET) scans, can detect signs of approaching disease and help pinpoint the preclinical window but are cumbersome or expensive. “There's no cheap, fast, noninvasive test that can identify people at risk of Alzheimer's,” says Brad Dolin, chief technology officer of Neurotrack in Palo Alto, Calif.—a company developing a computerized visual screening test for Alzheimer's. Unlike other cognitive batteries, the Neurotrack test requires no language or motor skills. Participants view images on a monitor while a camera tracks their eye movements. The test draws on research by co-founder Stuart Zola of Emory University, who studies learning and memory in monkeys. When presented with a pair of images—one novel, the other familiar—primates fixate longer on the novel one. But if the hippocampus is damaged, as it is in people with Alzheimer's, the subject does not show a clear preference for the novel images. © 2015 Scientific American
By ERICA GOODE A study suggests that newborn chicks map numbers spatially, associating low numerical values with space to their left. Credit Rosa Rugani/University of Padova Asked to picture the numbers from one to 10, most people will imagine a straight line with one at the left end and 10 at the right. This “mental number line,” as researchers have termed it, is so pervasive that some scientists have argued that the spatial representation of numbers is hard-wired into the brain, part of a primitive number system that underlies humans’ capacity for higher mathematics. Now a team of Italian researchers has found that newborn chicks, like humans, appear to map numbers spatially, associating smaller amounts with the left side and larger amounts with the right side. The chicks, trained to seek out mealworms behind white plastic panels printed with varying numbers of identical red squares, repeatedly demonstrated a preference for the left when the number of squares was small and for the right when the number was larger. The research, led by Rosa Rugani, a psychologist who at the time was at the University of Padova, will appear in Friday’s issue of the journal Science. Researchers demonstrated that chickens naturally order numbers left to right. When the number five is in the middle, chickens naturally go left for lower numbers and to the right for higher numbers. Publish Date January 29, 2015. In their report, the researchers said the findings supported the idea that the left-right orientation for numbers is innate rather than determined by culture or education — a possibility that was raised by some studies that found that in Arabic-speaking countries where letters and numbers are read right to left, the mental number scale was reversed. But the new research, Dr. Rugani and her colleagues wrote, indicates that orienting numbers in space may represent “a universal cognitive strategy available soon after birth.” Tyler Marghetis, a doctoral candidate in psychology at the University of California, San Diego, who has published research on the spatial association of numbers, called the researcher’s studies “very cool.” © 2015 The New York Times Company
by Clare Wilson Once only possible in an MRI scanner, vibrating pads and electrode caps could soon help locked-in people communicate on a day-to-day basis YOU wake up in hospital unable to move, to speak, to twitch so much as an eyelid. You hear doctors telling your relatives you are in a vegetative state – unaware of everything around you – and you have no way of letting anyone know this is not the case. Years go by, until one day, you're connected to a machine that allows you to communicate through your brain waves. It only allows yes or no answers, but it makes all the difference – now you can tell your carers if you are thirsty, if you'd like to sit up, even which TV programmes you want to watch. In recent years, breakthroughs in mind-reading technology have brought this story close to reality for a handful of people who may have a severe type of locked-in syndrome, previously diagnosed as being in a vegetative state. So far, most work has required a lab and a giant fMRI scanner. Now two teams are developing devices that are portable enough to be taken out to homes, to help people communicate on a day-to-day basis. The technology might also be able to identify people who have been misdiagnosed. People with "classic" locked-in syndrome are fully conscious but completely paralysed apart from eye movements. Adrian Owen of Western University in London, Canada, fears that there is another form of the condition where the paralysis is total. He thinks that a proportion of people diagnosed as being in a vegetative state – in which people are thought to have no mental awareness at all – are actually aware but unable to let anyone know. "The possibility is that we are missing people with some sort of complete locked-in syndrome," he says. © Copyright Reed Business Information Ltd.
Alison Abbott If you have to make a complex decision, will you do a better job if you absorb yourself in, say, a crossword puzzle instead of ruminating about your options? The idea that unconscious thought is sometimes more powerful than conscious thought is attractive, and echoes ideas popularized by books such as writer Malcolm Gladwell’s best-selling Blink. But within the scientific community, ‘unconscious-thought advantage’ (UTA) has been controversial. Now Dutch psychologists have carried out the most rigorous study yet of UTA — and find no evidence for it. Their conclusion, published this week in Judgement and Decision Making, is based on a large experiment that they designed to provide the best chance of capturing the effect should it exist, along with a sophisticated statistical analysis of previously published data1. The report adds to broader concerns about the quality of psychology studies and to an ongoing controversy about the extent to which unconscious thought in general can influence behaviour. “The bigger debate is about how clever our unconscious is,” says cognitive psychologist David Shanks of University College London. “This carefully constructed paper makes a great contribution.” Shanks published a review last year that questioned research claiming that various unconscious influences, including UTA, affect decision making2. © 2015 Nature Publishing Group
|By Christof Koch Faces are the glue that holds us together and that gives us our identity. All of us but the visually impaired and blind are experts at recognizing people's identity, gender, age and ethnicity from looking at their faces. First impressions of attractiveness or competence take but a brief glimpse of somebody's face. Newly born infants already tend to fixate on faces. This bias also turns up in art. Paintings and movies are filled with faces staring at the viewer. Who can forget the endless close-ups of the feuding husband and wife in Ingmar Bergman's Cimmerian masterpiece Scenes from a Marriage? Because recognizing a face is so vital to our social lives, it comes as no surprise that a lot of real estate in the cerebral cortex—the highly convoluted region that makes up the bulk of our brain—is devoted to a task crucial to processing faces and their identity. We note whether someone looks our way or not. We discern emotional expressions, whether they register joy, fear or anger. Indeed, functional brain imaging has identified a set of adjacent regions, referred to as the fusiform face area (FFA), that are situated on the left and the right sides of the brain, at the bottom of the temporal lobe of the cerebral cortex. The FFA turns up its activity when subjects look at portraits or close-ups of faces or even when they just think about these images. Two just published studies of the brain's visual networks, including the FFA, enlarge what we know about the physical basis of face perception. Both explore the unique access to the brain afforded by patients whose epileptic seizures have proved resistant to drugs. A surgical treatment finds the locations in the brain where the hypersynchronized activity that characterizes a seizure begins before spreading from its point of origin to engulf one or sometimes both hemispheres. If a single point—a focus where the seizure begins—can be found, it can be removed. After this procedure, a patient usually has significantly fewer seizures—and some remain seizure-free. To triangulate the location of the focus, neurosurgeons insert electrodes into the brain to monitor electrical activity that occurs during a seizure. © 2015 Scientific American
Link ID: 20523 - Posted: 01.27.2015
Simon Parkin A few months before she died, my grandmother made a decision. Bobby, as her friends called her (theirs is a generation of nicknames), was a farmer’s wife who not only survived World War II but also found in it justification for her natural hoarding talent. ‘Waste not, want not’ was a principle she lived by long after England recovered from a war that left it buckled and wasted. So she kept old envelopes and bits of cardboard cereal boxes for note taking and lists. She kept frayed blankets and musty blouses from the 1950s in case she needed material to mend. By extension, she was also a meticulous chronicler. She kept albums of photographs of her family members. She kept the airmail love letters my late grandfather sent her while he travelled the world with the merchant navy in a box. Her home was filled with the debris of her memories. Yet in the months leading up to her death, the emphasis shifted from hoarding to sharing. Every time I visited my car would fill with stuff: unopened cartons of orange juice, balls of fraying wool, damp, antique books, empty glass jars. All things she needed to rehome now she faced her mortality. The memories too began to move out. She sent faded photographs to her children, grandchildren and friends, as well as letters containing vivid paragraphs detailing some experience or other. On 9 April, the afternoon before the night she died, she posted a letter to one of her late husband’s old childhood friends. In the envelope she enclosed some photographs of my grandfather and his friend playing as young children. “You must have them,” she wrote to him. It was a demand but also a plea, perhaps, that these things not be lost or forgotten when, a few hours later, she slipped away in her favourite armchair. © 2015 BBC
Oliver Burkeman One spring morning in Tucson, Arizona, in 1994, an unknown philosopher named David Chalmers got up to give a talk on consciousness, by which he meant the feeling of being inside your head, looking out – or, to use the kind of language that might give a neuroscientist an aneurysm, of having a soul. Though he didn’t realise it at the time, the young Australian academic was about to ignite a war between philosophers and scientists, by drawing attention to a central mystery of human life – perhaps the central mystery of human life – and revealing how embarrassingly far they were from solving it. The scholars gathered at the University of Arizona – for what would later go down as a landmark conference on the subject – knew they were doing something edgy: in many quarters, consciousness was still taboo, too weird and new agey to take seriously, and some of the scientists in the audience were risking their reputations by attending. Yet the first two talks that day, before Chalmers’s, hadn’t proved thrilling. “Quite honestly, they were totally unintelligible and boring – I had no idea what anyone was talking about,” recalled Stuart Hameroff, the Arizona professor responsible for the event. “As the organiser, I’m looking around, and people are falling asleep, or getting restless.” He grew worried. “But then the third talk, right before the coffee break – that was Dave.” With his long, straggly hair and fondness for all-body denim, the 27-year-old Chalmers looked like he’d got lost en route to a Metallica concert. “He comes on stage, hair down to his butt, he’s prancing around like Mick Jagger,” Hameroff said. “But then he speaks. And that’s when everyone wakes up.”
Link ID: 20503 - Posted: 01.21.2015
Closing your eyes when trying to recall events increases the chances of accuracy, researchers at the University of Surrey suggest. Scientists tested people's ability to remember details of films showing fake crime scenes. They hope the studies will help witnesses recall details more accurately when questioned by police. They say establishing a rapport with the person asking the questions can also help boost memory. Writing in the journal Legal and Criminological Psychology, scientists tested 178 participants in two separate experiments. In the first, they asked volunteers to watch a film showing an electrician entering a property, carrying out work and then stealing a number of items. Volunteers were then questioned in one of four groups. People were either asked questions with their eyes open or closed, and after a sense of rapport had been built with the interviewer or no attempt had been made to create a friendly introduction. People who had some rapport with their interviewer and had their eyes shut throughout questioning answered three-quarters of the 17 questions correctly. But those who did not have a friendly introduction with the interviewer and had their eyes open answered 41% correctly. The analysis showed that eye closing had the strongest impact on remembering details correctly ,but that feeling comfortable during the interview also helped. In the second experiment, people were asked to remember details of what they had heard during a mock crime scene. © 2015 BBC
By Melissa Healy A pill may help those whose out-of-control eating is a cause of extreme distress An ADHD drug may offer hope for a different psychiatric disorder Binge eating disorder, a newly recognized condition in which bouts of voracious eating lead to guilt, shame and often obesity, may yield to lisdexamfetamine (marketed as Vyvanse), a medication that has been used for several years to treat attention deficit and hyperactivity disorder in children and adults. In an 11-week clinical trial that tested a range of Vyvanse dosages, researchers found that, compared to those taking a placebo pill, subjects diagnosed with binge eating disorder who took a daily 50 or 70 mg dose of the ADHD drug had fewer binge eating episodes, were more likely to cease binge eating for a four-week period, reported greater improvement in their functioning, and lost substantially more weight. The findings, published online early in the journal JAMA Psychiatry on Wednesday, offer early evidence that patients whose consumption patterns are punctuated by episodes of out-of-control eating may be helped by some medication. The disorder, which has in recent years won wider recognition by the psychiatric establishment, has traditionally been treated with psychotherapy. It has proved a difficult condition to treat. Among those getting lisdexamfetamine, side effects were similar to those experienced by adults who take the medication to treat symptoms of ADHD, including dry mouth, difficulty falling asleep, increased heart rate and headaches. Adverse events prompted six of 196 subjects in the active arm of treatment to withdraw from the study.
Keyword: Anorexia & Bulimia
Link ID: 20492 - Posted: 01.17.2015
By Peter Holley "Lynchian," according to David Foster Wallace, "refers to a particular kind of irony where the very macabre and the very mundane combine in such a way as to reveal the former's perpetual containment within the latter." Perhaps no other word better describes the onetime fate of Martin Pistorius, a South African man who spent more than a decade trapped inside his own body involuntarily watching "Barney" reruns day after day. "I cannot even express to you how much I hated Barney," Martin told NPR during the first episode of a new program on human behavior, "Invisibilia." The rest of the world thought Pistorius was a vegetable, according to NPR. Doctors had told his family as much after he'd fallen into a mysterious coma as a healthy 12-year-old before emerging several years later completely paralyzed, unable to communicate with the outside world. The nightmarish condition, which can be caused by stroke or an overdose of medication, is known as "total locked-in syndrome," and it has no cure, according to the National Institute of Neurological Disorders and Stroke. In a first-person account for the Daily Mail, Pistorius described the period after he slipped into a coma: I was completely unresponsive. I was in a virtual coma but the doctors couldn’t diagnose what had caused it. When he finally did awaken in the early 1990s, around the age of 14 or 15, Pistorius emerged in a dreary fog as his mind gradually rebooted itself.
Ewen Callaway The ability to recognize oneself in a mirror has been touted as a hallmark of higher cognition — present in humans and only the most intelligent of animals — and the basis for empathy. A study published this week in Current Biology controversially reports that macaques can be trained to pay attention to themselves in a mirror, the first such observation in any monkey species1. Yet the finding raises as many questions as it answers — not only about the cognitive capacity of monkeys, but also about mirror self-recognition as a measure of animal intelligence. “Simply because you’re acting as if you recognize yourself in a mirror doesn’t necessarily mean you’ve achieved self-recognition,” says Gordon Gallup, an evolutionary psychologist at the State University of New York in Albany, who in 1970 was the first to demonstrate mirror self-recognition in captive chimpanzees2. When most animals encounter their reflections in a mirror, they act as if they have seen another creature. They lash out aggressively, belt out loud calls and display other social behaviours. This is how chimps first acted when Gallup placed a full-length mirror next to their cages. But after a couple of days, their attitudes changed and they started examining themselves, says Gallup. “They’d look at the inside of their mouths; they’d watch their tongue move.” This convinced him that the chimps recognized themselves in the mirror. He knew other scientists would be sceptical, so he developed a test of mirror self-recognition. After chimps started acting as if they saw themselves in the mirror, after about 10 days, he anaesthetized them and applied an odour-free red mark to a location on their faces they could not see, such as above the brow ridge. © 2015 Nature Publishing Group
Link ID: 20467 - Posted: 01.10.2015