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|By Gary Stix A biochemical produced in the brain called oxytocin has entered popular culture in recent years as the “love,” “cuddle” or “bonding” hormone. That’s a lot to choose from. Oxytocin plays a role in producing contractions at childbirth and in helping in lactation, but we’ve known that for more than a century. Experiments in the 1990s showed that it was instrumental in leading prairie voles, known for their monogamous behavior, to pick a lifelong mate. Later studies then demonstrated that the chemical contributes to trust and social interactions in various animals, including humans. After the vole study, interest in the nine–amino acid peptide started to rise. In a TED talk economist Paul Zak called it “the moral molecule” because of its link to trust, empathy and prosperity. The Internet DIY brain-makeover market then took up the meme. Vero Labs of Daytona Beach, Fla., sells “Connekt” oxytocin spray for $79 that purports to “strengthen workplace bonds” and “increase positive self-awareness.” The company has also come out with a his-and-her“Attrakt” spray that mixes oxytocin with pheromones—chemical sex attractants that help mice get it on, but whose role in triggering mating behavior in humans is hotly disputed. (Researchers who study oxytocin warn prospective buyers away from these purchases, saying that long-term use in humans has not been studied.) © 2014 Scientific American

Keyword: Hormones & Behavior; Aggression
Link ID: 20053 - Posted: 09.10.2014

By SOMINI SENGUPTA A coalition of political figures from around the world, including Kofi Annan, the former United Nations secretary general, and several former European and Latin American presidents, is urging governments to decriminalize a variety of illegal drugs and set up regulated drug markets within their own countries. The proposal by the group, the Global Commission on Drug Policy, goes beyond its previous call to abandon the nearly half-century-old American-led war on drugs. As part of a report scheduled to be released on Tuesday, the group goes much further than its 2011 recommendation to legalize cannabis. The former Brazilian president Fernando Henrique Cardoso, a member of the commission, said the group was calling for the legal regulation of “as many of the drugs that are currently illegal as possible, with the understanding that some drugs may remain too dangerous to decriminalize.” The proposal comes at a time when several countries pummeled by drug violence, particularly in Latin America, are rewriting their own drug laws, and when even the United States is allowing state legislatures to gingerly regulate cannabis use. The United Nations is scheduled to hold a summit meeting in 2016 to evaluate global drug laws. The commission includes former presidents like Mr. Cardoso of Brazil, Ernesto Zedillo of Mexico and Ruth Dreifuss of Switzerland, along with George P. Shultz, a former secretary of state in the Reagan administration, among others. The group stops short of calling on countries to legalize all drugs right away. It calls instead for countries to continue to pursue violent criminal gangs, to stop incarcerating users and to offer treatment for addicts. © 2014 The New York Times Company

Keyword: Drug Abuse
Link ID: 20052 - Posted: 09.10.2014

By Mo Costandi The nerve endings in your fingertips can perform complex neural computations that were thought to be carried out by the brain, according to new research published in the journal Nature Neuroscience. The processing of both touch and visual information involves computations that extract the geometrical features of objects we touch and see, such as the edge orientation. Most of this processing takes place in the brain, which contains cells that are sensitive to the orientation of edges on the things we touch and see, and which pass this information onto cells in neighbouring regions, that encode other features. The brain has outsourced some aspects of visual processing, such as motion detection, to the retina, and the new research shows that something similar happens in the touch processing pathway. Delegating basic functions to the sense organs in this way could be an evolutionary mechanism that enables the brain to perform other, more sophisticated information processing tasks more efficiently. Your fingertips are among the most sensitive parts of your body. They are densely packed with thousands of nerve endings, which produce complex patterns of nervous impulses that convey information about the size, shape and texture of objects, and your ability to identify objects by touch and manipulate them depends upon the continuous influx of this information. © 2014 Guardian News and Media Limited

Keyword: Pain & Touch
Link ID: 20051 - Posted: 09.09.2014

Ewen Callaway Researchers found 69 genes that correlate with higher educational attainment — and three of those also also appear to have a direct link to slightly better cognitive abilities. Scientists looking for the genes underlying intelligence are in for a slog. One of the largest, most rigorous genetic study of human cognition1 has turned up inconclusive findings, and experts concede that they will probably need to scour the genomes of more than 1 million people to confidently identify even a small genetic influence on intelligence and other behavioural traits. Studies of twins have repeatedly confirmed a genetic basis for intelligence, personality and other aspects of behaviour. But efforts to link IQ to specific variations in DNA have led to a slew of irreproducible results. Critics have alleged that some of these studies' methods were marred by wishful thinking and shoddy statistics. A sobering editorial in the January 2012 issue of Behavior Genetics2 declared that “it now seems likely that many of the published findings of the last decade are wrong or misleading and have not contributed to real advances in knowledge”. In 2011, an international collaboration of researchers launched an effort to bring more rigour to studies of how genes contribute to behaviour. The group, called the Social Sciences Genetic Association Consortium, aimed to do studies using practices borrowed from the medical genetics community, which emphasizes large numbers of participants, rigorous statistics and reproducibility. In a 2013 study3 comparing the genomes of more than 126,000 people, the group identified three gene variants associated with with how many years of schooling a person had gone through or whether they had attended university. But the effect of these variants was small — each variant correlated with roughly one additional month of schooling in people who had it compared with people who did not. © 2014 Nature Publishing Group

Keyword: Intelligence; Aggression
Link ID: 20050 - Posted: 09.09.2014

By Jena McGregor We've all heard the conventional wisdom for better managing our time and organizing our professional and personal lives. Don't try to multitask. Turn the email and Facebook alerts off to help stay focused. Make separate to-do lists for tasks that require a few minutes, a few hours and long-term planning. But what's grounded in real evidence and what's not? In his new book The Organized Mind, Daniel Levitin — a McGill University professor of psychology and behavioral neuroscience — explores how having a basic understanding of the way the brain works can help us think about organizing our homes, our businesses, our time and even our schools in an age of information overload. We spoke with Levitin about why multi-tasking never works, what images of good leaders' brains actually look like, and why email and Twitter are so incredibly addicting. The following transcript of our conversation has been edited for length and clarity. Q. What was your goal in writing this book? A. Neuroscientists have learned a lot in the last 10 or 15 years about how the brain organizes information, and why we pay attention to some things and forget others. But most of this information hasn't trickled down to the average reader. There are a lot of books about how to get organized and a lot of books about how to be better and more productive at business, but I don't know of one that grounds any of these in the science.

Keyword: Attention
Link ID: 20049 - Posted: 09.09.2014

By C. CLAIBORNE RAY Q. Is there a difference between alcoholic dementia and “regular” dementia in the elderly? A. Dementia refers to the general category of diseases that cause acquired cognitive loss, usually in later life, said Dr. Mark S. Lachs, director of geriatrics for the NewYork-Presbyterian Healthcare System. Such loss has scores of possible causes, he said, but Alzheimer’s disease is the culprit in a vast majority of cases in the developed world. Alzheimer’s and what doctors call alcohol-related dementia affect parts of the brain cortex that control memory, language and the ability to follow motor commands. Because Alzheimer’s and excessive drinking are relatively common in the older population and can occur at the same time, and because many of their clinical features overlap and affect similar parts of the brain, “it is more accurate to say that each condition potentially exacerbates the other,” Dr. Lachs said. Abstinence is the treatment of choice in alcohol-related dementia, with or without concurrent Alzheimer’s disease or another form of dementia. Even in patients with “pure” Alzheimer’s disease or another kind of dementia, Dr. Lachs said, most experts recommend greatly moderating alcohol consumption or eliminating it, as even occasional drinking “can serve as a brain stress test for a patient with impaired cognition from any cause.” © 2014 The New York Times Company

Keyword: Alzheimers; Aggression
Link ID: 20048 - Posted: 09.09.2014

By Maggie Fox, Erika Edwards and Judy Silverman Here’s how you might be able to turn autism around in a baby: Carefully watch her cues, and push just a little harder with that game of peek-a-boo or “This little piggy.” But don’t push too hard — kids with autism are super-sensitive. That’s what Sally Rogers of the University of California, Davis has found in an intense experiment with the parents of infants who showed clear signs of autism. It’s one of the most hopeful signs yet that if you diagnose autism very early, you can help children rewire their brains and reverse the symptoms. It was a small study, and it’s very hard to find infants who are likely to have autism, which is usually diagnosed in the toddler years. But the findings, published in the Journal of Autism and Developmental Disorders, offer some hope to parents worried about their babies. “With only seven infants in the treatment group, no conclusions can be drawn,” they wrote. However, the effects were striking. Six out of the seven children in the study had normal learning and language skills by the time they were 2 to 3. Isobel was one of them. “She is 3 years old now and she is a 100 percent typical, normally developing child,” her mother, Megan, told NBC News. The family doesn’t want their last name used for privacy reasons. “We don’t have to do the therapy any more. It literally rewired her brain.” Autism is a very common diagnosis for children in the U.S. The latest survey by the Centers for Disease Control and Prevention shows a startling 30 percent jump among 8-year-olds diagnosed with the disorder in a two-year period, to one in every 68 children.

Keyword: Autism
Link ID: 20047 - Posted: 09.09.2014

// by Richard Farrell Conventional thinking has long held that pelvic bones in whales and dolphins, evolutionary throwbacks to ancestors that once walked on land, are vestigial and will disappear millions of years from now. But researchers from University of Southern California and the Natural History Museum of Los Angeles County (NHM) have upended that assumption. The scientists argue in a paper just published in the journal Evolution that cetacean (whale and dolphin) pelvic bones certainly do have a purpose and that they're specifically targeted, by selection, for mating. The muscles that control a cetacean's penis are attached to the creature's pelvic bones. Matthew Dean, assistant professor at the USC Dornsife College of Letters, Arts and Sciences, and Jim Dines, collections manager of mammalogy at NHM, wanted to find out if pelvic bones could be evolutionarily advantageous by impacting the overall amount of control an individual creature has with its penis. The pair spent four years examining whale and dolphin pelvic bones, using a 3D laser scanner to study the shape and size of the samples in extreme detail. Then they gathered as much data as they could find -- reaching back to whaler days -- on whale testis size relative to body mass. The testis data was important because in nature, species in "promiscuous," competitive mating environments (where females mate with multiple males) develop larger testes, relative to their body mass, in order to outdo the competition. © 2014 Discovery Communications, LLC.

Keyword: Evolution; Aggression
Link ID: 20046 - Posted: 09.09.2014

By MICHAEL HEDRICK I can remember the early days of having schizophrenia. I was so afraid of the implications of subtle body language, like a lingering millisecond of eye contact, the way my feet hit the ground when I walked or the way I held my hands to my side. It was a struggle to go into a store or, really, anywhere I was bound to see another living member of the human species. With a simple scratch of the head, someone could be telling me to go forward, or that what I was doing was right or wrong, or that they were acknowledging the symbolic crown on my head that made me a king or a prophet. It’s not hard to imagine that I was having a tough time in the midst of all the anxiety and delusions. Several months after my diagnosis, I took a job at a small town newspaper as a reporter. I sat in on City Council meetings, covering issues related to the lowering water table and interviewing local business owners for small blurbs in the local section, all the while wondering if I was uncovering some vague connections to an international conspiracy. The nights were altogether different. Every day, I would come home to my apartment and smoke pot, then lay on my couch watching television or head out to the bar and get so hammered that I couldn’t walk. It’s hard to admit, but the only time I felt relaxed was when I was drunk. I eventually lost my newspaper job, but that wasn’t the catalyst for change. It all came to a head one night in July. I had been out drinking all night and, in a haze, I decided it would be a good idea to drive the two miles back to my apartment. This is something I had done several times before, but it had never dawned on me that it was a serious deal. I thought I was doing well, not swerving and being only several blocks from my house, when I saw flashing lights behind me. What started as a trip to the bar to unwind ended with me calling my parents to bail me out of jail at 3 a.m. © 2014 The New York Times Company

Keyword: Schizophrenia; Aggression
Link ID: 20045 - Posted: 09.08.2014

Being bullied regularly by a sibling could put children at risk of depression when they are older, a study led by the University of Oxford suggests. Around 7,000 children aged 12 were asked if they had experienced a sibling saying hurtful things, hitting, ignoring or lying about them. The children were followed up at 18 and asked about their mental health. A charity said parents should deal with sibling rivalry before it escalates. Previous research has suggested that victims of peer bullying can be more susceptible to depression, anxiety and self-harm. This study claims to be the first to examine bullying by brothers or sisters during childhood for the same psychiatric problems in early adulthood. Researchers from the Universities of Oxford, Warwick and Bristol and University College London sent questionnaires to thousands of families with 12-year-old children in 2003-04 and went back to them six years later to assess their mental health. If they had siblings they were asked about bullying by brothers and sisters. The questionnaire said: "This means when a brother or sister tries to upset you by saying nasty and hurtful things, or completely ignores you from their group of friends, hits, kicks, pushes or shoves you around, tells lies or makes up false rumours about you." Most children said they had not experienced bullying. Of these, at 18, 6.4% had depression scores in the clinically significant range, 9.3% experienced anxiety and 7.6% had self-harmed in the previous year. The 786 children who said they had been bullied by a sibling several times a week were found to be twice as likely to have depression, self-harm and anxiety as the other children. BBC © 2014

Keyword: Depression; Aggression
Link ID: 20044 - Posted: 09.08.2014

By BENEDICT CAREY Imagine that on Day 1 of a difficult course, before you studied a single thing, you got hold of the final exam. The motherlode itself, full text, right there in your email inbox — attached mistakenly by the teacher, perhaps, or poached by a campus hacker. No answer key, no notes or guidelines. Just the questions. Would that help you study more effectively? Of course it would. You would read the questions carefully. You would know exactly what to focus on in your notes. Your ears would perk up anytime the teacher mentioned something relevant to a specific question. You would search the textbook for its discussion of each question. If you were thorough, you would have memorized the answer to every item before the course ended. On the day of that final, you would be the first to finish, sauntering out with an A+ in your pocket. And you would be cheating. But what if, instead, you took a test on Day 1 that was just as comprehensive as the final but not a replica? You would bomb the thing, for sure. You might not understand a single question. And yet as disorienting as that experience might feel, it would alter how you subsequently tuned into the course itself — and could sharply improve your overall performance. This is the idea behind pretesting, one of the most exciting developments in learning-­science. Across a variety of experiments, psychologists have found that, in some circumstances, wrong answers on a pretest aren’t merely useless guesses. Rather, the attempts themselves change how we think about and store the information contained in the questions. On some kinds of tests, particularly multiple-choice, we benefit from answering incorrectly by, in effect, priming our brain for what’s coming later. That is: The (bombed) pretest drives home the information in a way that studying as usual does not. We fail, but we fail forward. © 2014 The New York Times Company

Keyword: Learning & Memory
Link ID: 20043 - Posted: 09.08.2014

by Laura Beil The obesity crisis has given prehistoric dining a stardom not known since Fred Flintstone introduced the Bronto Burger. Last year, “Paleo diet” topped the list of most-Googled weight loss searches, as modern Stone Age dieters sought the advice of bestsellers like The Paleo Solution or The Primal Blueprint, which encourages followers to “honor your primal genes.” The assumption is that America has a weight problem because human metabolism runs on ancient genes that are ill equipped for contemporary eating habits. In this line of thinking, a diet true to the hunter-gatherers we once were — heavy on protein, light on carbs — will make us skinny again. While the fad has attracted skepticism from those who don’t buy the idea whole hog, there’s still plenty of acceptance for one common premise about the evolution of obesity: Our bodies want to stockpile fat. For most of human history, the theory goes, hunter-gatherers ate heartily when they managed to slay a fleeing mastodon. Otherwise, prehistoric life meant prolonged stretches of near starvation, surviving only on inner reserves of adipose. Today, modern humans mostly hunt and gather at the drive-thru, but our Pleistocene genes haven’t stopped fretting over the coming famine. The idea that evolution favored calorie-hoarding genes has long shaped popular and scientific thinking. Called the “thrifty gene” hypothesis, it has arguably been the dominant theory for evolutionary origins of obesity, and by extension diabetes. (Insulin resistance and diabetes so commonly accompany obesity that doctors have coined the term “diabesity.”) However, it’s not that difficult to find scientists who call the rise of the thrifty gene theory a feat of enthusiasm over evidence. Greg Gibson, director of the Center for Integrative Genomics at Georgia Tech in Atlanta, calls the data “somewhere between scant and nonexistent — a great example of crowd mentality in science.” © Society for Science & the Public 2000 - 2014

Keyword: Obesity
Link ID: 20042 - Posted: 09.06.2014

By Jeffrey Mervis Embattled U.K. biomedical researchers are drawing some comfort from a new survey showing that a sizable majority of the public continues to support the use of animals in research. But there’s another twist that should interest social scientists as well: The government’s decision this year to field two almost identical surveys on the topic offers fresh evidence that the way you ask a question affects how people answer it. Since 1999, the U.K. Department for Business, Innovation & Skills (BIS) has been funding a survey of 1000 adults about their attitudes toward animal experimentation. But this year the government asked the London-based pollsters, Ipsos MORI, to carry out a new survey, changing the wording of several questions. (The company also collected additional information, including public attitudes toward different animal species and current rules regarding their use.) For example, the phrase “animal experimentation” was replaced by “animal research” because the latter is “less inflammatory,” notes Ipsos MORI Research Manager Jerry Latter. In addition, says Emma Brown, a BIS spokeswoman, the word research “more accurately reflects the range of procedures that animals may be involved in, including the breeding of genetically modified animals.” But government officials also value the information about long-term trends in public attitudes that can be gleaned from the current survey. So they told the company to conduct one last round—the 10th in the series—at the same time they deployed the new survey. Each survey went to a representative, but different, sample of U.K. adults. © 2014 American Association for the Advancement of Scienc

Keyword: Animal Rights
Link ID: 20041 - Posted: 09.06.2014

Ewen Callaway Caffeine's buzz is so nice it evolved twice. The coffee genome has now been published, and it reveals that the coffee plant makes caffeine using a different set of genes from those found in tea, cacao and other perk-you-up plants. Coffee plants are grown across some 11 million hectares of land, with more than two billion cups of the beverage drunk every day. It is brewed from the fermented, roasted and ground berries of Coffea canephora and Coffea arabica, known as robusta and arabica, respectively. An international team of scientists has now identified more than 25,000 protein-making genes in the robusta coffee genome. The species accounts for about one-third of the coffee produced, much of it for instant-coffee brands such as Nescafe. Arabica contains less caffeine, but its lower acidity and bitterness make it more flavourful to many coffee drinkers. However, the robusta species was selected for sequencing because its genome is simpler than arabica’s. Caffeine evolved long before sleep-deprived humans became addicted to it, probably to defend the coffee plant against predators and for other benefits. For example, coffee leaves contain the highest levels of caffeine of any part of the plant, and when they fall on the soil they stop other plants from growing nearby. “Caffeine also habituates pollinators and makes them want to come back for more, which is what it does to us, too,” says Victor Albert, a genome scientist at the University of Buffalo in New York, who co-led the sequencing effort. The results were published on 4 September in Science1. © 2014 Nature Publishing Group

Keyword: Drug Abuse; Aggression
Link ID: 20040 - Posted: 09.06.2014

By S. Matthew Liao As many as 20 percent of war veterans return from combat in Afghanistan and Iraq with post-traumatic stress disorder (PTSD) or major depression, according to a 2008 report from the RAND Corporation. Many experience constant nightmares and flashbacks and many can’t live normal lives. For significant number of veterans, available medications do not seem to help. In 2010, at least 22 veterans committed suicide each day, according to the Department of Veterans Affairs. In her book, Demon Camp, the author Jen Percy describes damaged veterans who have even resorted to exorcism to alleviate their PTSD symptoms. As part of President Obama’s BRAIN Initiative, the federal Defense Advanced Research Projects Agency (DARPA) plans to spend more than $70 million over five years to develop novel devices that would address neurological disorders such as PTSD. DARPA is particularly interested in a technology called Deep Brain Stimulation (DBS). DBS involves inserting a thin electrode through a small opening in the skull into a specific area in the brain; the electrode is then connected by an insulated wire to a battery pack underneath the skin; the battery pack then sends electrical pulses via the wire to the brain. About 100,000 people around the world today have a DBS implant to ameliorate the effects of Parkinson’s disease, epilepsy and major depression. There is evidence that DBS can also help with PTSD. Functional neuroimaging studies indicate that amygdala hyperactivity is responsible for the symptoms of PTSD and that DBS can functionally reduce the activity of the amygdala. In animal PTSD models, DBS has been found to be more effective than current treatment using selective serotonin reuptake inhibitors. © 2014 Scientific American

Keyword: Stress
Link ID: 20039 - Posted: 09.06.2014

By Tanya Lewis, In an experiment that sounds more like science fiction than reality, two humans were able to send greetings to each other using only a digital connection linking their brains. Using noninvasive means, researchers made brain recordings of a person in India thinking the words "hola" and "ciao," and then decoded and emailed the messages to France, where a machine converted the words into brain stimulation in another person, who perceived the signals as flashes of light. From the sequence of flashes, the French recipient was able to successfully interpret the greetings, according to a new study published today (Sept. 5) in the journal PLOS ONE. The researchers wanted to know if it is possible for two people to communicate by reading out the brain activity of one person and injecting that activity into a second person. "Could we develop an experiment that would bypass the talking or typing part of [the] Internet and establish direct brain-to-brain communication between subjects located far away from each other, in India and France?" co-author Dr. Alvaro Pascual-Leone said in a statement. Pascual-Leone is a neurologist at Beth Israel Deaconess Medical Center in Boston, and a professor at Harvard Medical School, in Cambridge, Massachusetts. To answer that question, Pascual-Leone and his colleagues at Starlab Barcelona, in Spain, and Axilum Robotics, in Strasbourg, France, turned to several widely used brain technologies. Electroencephalogram, or EEG, recordings are taken by placing a cap of electrodes on a person's scalp, and recording the electrical activity of large regions of the brain's cortex. Previous studies have recorded EEG from a person thinking about an action, such as moving his or her arm, while a computer translates the signal into an output used to move a robotic exoskeleton or drive a wheelchair.

Keyword: Brain imaging; Aggression
Link ID: 20038 - Posted: 09.06.2014

By LISA SANDERS, M.D. On Thursday, we challenged Well readers to take on the case of a 19-year-old man who suddenly collapsed at work after months of weakness and fatigue dotted with episodes of nausea and vomiting. More than 500 of you wrote in with suggested diagnoses. And more than 60 of you nailed it. The cause of this man’s collapse, weakness, nausea and vomiting was… Addisonian crisis because of Addison’s disease Addison’s disease, named after Dr. Thomas Addison, the 19th-century physician who first described the disorder, occurs when the adrenal glands stop producing the fight-or-flight hormones, particularly cortisol and adrenaline and a less well known but equally important hormone called aldosterone that helps the body manage salt. In Addison’s, the immune system mistakenly attacks the adrenal glands as if they were foreign invaders. Why this happens is not well understood, but without these glands and the essential hormones they make, the body cannot respond to biological stress. The symptoms of Addison’s are vague. That’s one reason it’s so hard to diagnosis. Patients complain of weakness and fatigue. They often crave salt. And when confronted with any stress — an infection or an injury — patients with Addison’s may go into adrenal crisis, characterized by nausea and vomiting, low blood pressure and, sometimes, physical collapse. Their blood pressure may drop so low that oxygen-carrying blood cannot reach the extremities, causing skin to turn blue; if blood fails to reach even more essential organs, it can lead to death. © 2014 The New York Times Company

Keyword: Hormones & Behavior
Link ID: 20037 - Posted: 09.06.2014

On 5th May, 1953, the novelist Aldous Huxley dissolved four-tenths of a gram of mescaline in a glass of water, drank it, then sat back and waited for the drug to take effect. Huxley took the drug in his California home under the direct supervision of psychiatrist Humphry Osmond, to whom Huxley had volunteered himself as “a willing and eager guinea pig”. Osmond was one of a small group of psychiatrists who pioneered the use of LSD as a treatment for alcoholism and various mental disorders in the early 1950s. He coined the term psychedelic, meaning ‘mind manifesting’ and although his research into the therapeutic potential of LSD produced promising initial results, it was halted during the 1960s for social and political reasons. Born in Surrey in 1917, Osmond studied medicine at Guy’s Hospital, London. He served in the navy as a ship’s psychiatrist during World War II, and afterwards worked in the psychiatric unit at St. George’s Hospital, London, where he became a senior registrar. While at St. George’s, Osmond and his colleague John Smythies learned about Albert Hoffman’s discovery of LSD at the Sandoz Pharmaceutical Company in Bazel, Switzerland. Osmond and Smythies started their own investigation into the properties of hallucinogens and observed that mescaline produced effects similar to the symptoms of schizophrenia, and that its chemical structure was very similar to that of the hormone and neurotransmitter adrenaline. This led them to postulate that schizophrenia was caused by a chemical imbalance in the brain, but these ideas were not favourably received by their colleagues. In 1951 Osmond took a post as deputy director of psychiatry at the Weyburn Mental Hospital in Saskatchewan, Canada and moved there with his family. Within a year, he began collaborating on experiments using LSD with Abram Hoffer. Osmond tried LSD himself and concluded that the drug could produce profound changes in consciousness. Osmond and Hoffer also recruited volunteers to take LSD and theorised that the drug was capable of inducing a new level of self-awareness which may have enormous therapeutic potential. © 2014 Guardian News and Media Limited

Keyword: Drug Abuse; Aggression
Link ID: 20036 - Posted: 09.04.2014

by Sandrine Ceurstemont Screening an instructional monkey movie in a forest reveals that marmosets do not only learn from family members: they also copy on-screen strangers. It is the first time such a video has been used for investigations in the wild. Tina Gunhold at the University of Vienna, Austria, and her colleagues filmed a common marmoset retrieving a treat from a plastic device. They then took the device to the Atlantic Forest near Aldeia in Pernambuco, Brazil, and showed the movie to wild marmosets there. Although monkeys are known to learn from others in their social group, especially when they are youngMovie Camera, little is known about their ability to learn from monkeys that do not belong to the same group. Marmosets are territorial, so the presence of an outsider – even a virtual one on a screen – could provoke an attack. "We didn't know if wild marmosets would be frightened of the video box but actually they were all attracted to it," says Gunhold. Compared to monkeys shown a static image of the stranger, video-watching marmosets were more likely to manipulate the device, typically copying the technique shown (see video). Young monkeys spent more time near the video box than older family members, suggesting that they found the movie more engaging – although as soon as one monkey mastered the task, it was impossible to tell whether the others were learning from the video or from their relative. "We think it's a combination of both," says Gunhold. © Copyright Reed Business Information Ltd.

Keyword: Learning & Memory; Aggression
Link ID: 20035 - Posted: 09.04.2014

By Fredrick Kunkle Years ago, many scientists assumed that a woman’s heart worked pretty much the same as a man’s. But as more women entered the male-dominated field of cardiology, many such assumptions vanished, opening the way for new approaches to research and treatment. A similar shift is underway in the study of Alzheimer’s disease. It has long been known that more women than men get the deadly neurodegenerative disease, and an emerging body of research is challenging the common wisdom as to why. Although the question is by no means settled, recent findings suggest that biological, genetic and even cultural influences may play heavy roles. Of the more than 5 million people in the United States who have been diagnosed with Alzheimer’s, the leading cause of dementia, two-thirds are women. Because advancing age is considered the biggest risk factor for the disease, researchers largely have attributed that disparity to women’s longer life spans. The average life expectancy for women is 81 years, compared with 76 for men. Yet “even after taking age into account, women are more at risk,” said Richard Lipton, a physician who heads the Einstein Aging Study at Albert Einstein College of Medicine in New York. With the number of Alzheimer’s cases in the United States expected to more than triple by 2050, some researchers are urging a greater focus on understanding the underlying reasons women are more prone to the disease and on developing gender-specific treatments. The area of inquiry has been growing in part because of a push by female Alzheimer’s researchers, who have formed a group to advocate for a larger leadership role in the field and more gender-specific research.

Keyword: Alzheimers; Aggression
Link ID: 20034 - Posted: 09.04.2014