Chapter 9. Hearing, Vestibular Perception, Taste, and Smell

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By Ryan P. Dalton Subject cDa29—well-known yet anonymous—resides somewhere in the north of England. You can almost see it: the peat stacks and old textile mills; the limestone and turf ruins where, on divine calling, Hadrian marked the northernmost reach of the Roman Empire. But even were you there, you wouldn’t see it the way cDa29 does. That’s because cDa29 is tetrachromatic: while most people see their world as a mix of three colors—red, green and blue—cDa29 sees hers in four. Difficult to imagine as that world may be for trichromats, your sense of smell provides access to an even richer world, one painted not in four colors but 400. You can almost smell it: the peat, the mills, the turf. How do your senses build these worlds? They begin with sensory “receptors,” which sit on the surfaces of cells and are activated by specific stimuli. In the case of vision, there are three color photoreceptors in your retina—activated by red, green or blue light. By keeping these receptors separated—such that no two photoreceptors occur together in one cell—your retina can keep track of what colors came from where. As a counterexample, you have a few dozen “bitter receptors” on your tongue, but each bitter taste cell contains several of them. This arrangement allows you to detect many different bitter compounds, but it does not help you distinguish between them. As these examples illustrate, you must both be able to detect a wide range of stimuli and to discriminate between those stimuli—and generally, your senses strike a balance between these two objectives. Ever the romantic, your sense of smell casts aside the suggestion of balance and optimizes for both detection and discrimination. Olfactory neurons in your nose have evolved some 400 odor receptors, and each neuron contains only one. Receptors are tuned to detect a few basic odors apiece: some detect geranium petals or pine needles, while others detect the by-products of putrefaction. To organize all this information, your olfactory neurons wire into an “olfactory map” on your brain’s olfactory bulb. Olfactory neurons are one of the few types of neurons that are born throughout your life, and each of the roughly 10,000 such neurons born each day in your nose subsequently wires into the olfactory map in your brain. © 2019 Scientific American

Keyword: Chemical Senses (Smell & Taste)
Link ID: 26492 - Posted: 08.13.2019

Sacha Pfeiffer There's a new smell tingling tourists' noses in the Big Apple, far above the trash bag-lined sidewalks — and this scent is by design. Atop One World Trade Center, New York City's tallest building, a fragrance carrying hints of citrus, beech trees and red maples wafts through the glass-enclosed observatory deck. When the observatory commissioned the custom scent to diffuse through the floor's HVAC system, Managing Director Keith Douglas told the New York Times that he wanted it to elicit a "positive thought," and offer a "a subtle complement to the experience" of visiting the space. But not everyone is keen on the scent. One tourist described the smell as "sickly," according to the Times, which first documented the new aromatic experience in lower Manhattan. It's a marketing strategy businesses are increasingly deploying to lure customers into stores and entice them to stay longer. The smell of cinnamon fills Yankee Candle stores, Subway pumps a doughy bread scent through its vents. International Flavors & Fragrances, the same company that developed clothing chain Abercrombie & Fitch's notoriously pungent "Fierce" cologne, known to linger on clothes long after their purchase, designed One World's scent. "The quickest way to change somebody's mood or behavior is with smell," says Dr. Alan Hirsch, neurological director of the Smell and Taste Treatment and Research Foundation in Chicago. © 2019 npr

Keyword: Chemical Senses (Smell & Taste); Emotions
Link ID: 26487 - Posted: 08.12.2019

Ian Sample Science editor When Snowball the sulphur-crested cockatoo revealed his first dance moves a decade ago he became an instant sensation. The foot-tapping, head-bobbing bird boogied his way on to TV talkshows and commercials and won an impressive internet audience. Block-rocking beaks: Snowball the cockatoo – reviewed by our dance critic Read more But that was merely the start. A new study of the prancing parrot points to a bird at the peak of his creative powers. In performances conducted from the back of an armchair, Snowball pulled 14 distinct moves – a repertoire that would put many humans to shame. Footage of Snowball in action shows him smashing Another One Bites the Dust by Queen and Cyndi Lauper’s Girls Just Wanna Have Fun with a dazzling routine of head-bobs, foot-lifts, body-rolls, poses and headbanging. In one move, named the Vogue, Snowball moves his head from one side of a lifted foot to another. “We were amazed,” said Aniruddh Patel, a psychology professor at Tufts University in Medford, Massachusetts. “There are moves in there, like the Madonna Vogue move, that I just can’t believe.” Advertisement “It seems that dancing to music isn’t purely a product of human culture. The fact that we see this in another animal suggests that if you have a brain with certain cognitive and neural capacities, you are predisposed to dance,” he added. It all started, as some things must, with the Backstreet Boys. In 2008, Patel, who has long studied the origins of musicality, watched a video on the internet of Snowball dancing in time to the band’s track Everybody. He contacted Irena Schulz, who owned the bird shelter where Snowball lived, and with her soon launched a study of Snowball’s dancing prowess. © 2019 Guardian News & Media Limited

Keyword: Hearing; Evolution
Link ID: 26400 - Posted: 07.09.2019

By Richard Klasco, M.D. Q. Please explain positional vertigo. Two of my siblings have woken up in the morning with it. What do you do if you experience it? A. Positional vertigo is a common type of dizziness that can be treated with a simple maneuver. Vertigo is an illusory sensation of motion that is often accompanied by intense nausea. Benign paroxysmal positional vertigo, or B.P.P.V., is the medical term for positional vertigo. It is important to use this term, as there are other types of vertigo with different causes and treatments. B.P.P.V. is caused by microscopic “stones” that are present on the ends of hair follicles in the ear canal and that help you maintain your balance. Vertigo occurs when these stones break off and move from the body of the inner ear into its semicircular canals, which determine our perception of three-dimensional space. This usually occurs as a result of aging or head trauma. Free-floating stones cause the inner ear to give faulty information to the brain about our position in space, creating a false sensation of motion. The mechanism of B.P.P.V. was discovered almost a century ago by the Viennese physician Dr. Robert Bárány, who won a Nobel Prize for his work. In 1979, Dr. John Epley, an ear, nose and throat specialist in Portland, Ore., found that a simple maneuver could treat most cases of B.P.P.V. without the need for drugs or surgery. The Epley maneuver is a series of rapid changes in position of the head that are performed in a doctor’s office. The maneuver repositions stones so they do not cause symptoms. Incidentally, B.P.P.V. has been reported to be cured in some people after they have ridden on roller coasters. © 2019 The New York Times Company

Keyword: Miscellaneous
Link ID: 26365 - Posted: 06.28.2019

By Matthew Hutson LONG BEACH, CALIFORNIA—Spies may soon have another tool to carry out their shadowy missions: a new device that uses sound to “see” around corners. David Lindell Previously, researchers developed gadgets that bounced light waves around corners to catch reflections and see things out of the line of sight. To see whether they could do something similar with sound, another group of scientists built a hardware prototype—a vertical pole adorned with off-the-shelf microphones and small car speakers. The speakers emitted a series of chirps, which bounced off a nearby wall at an angle before hitting a hidden object on another wall—a poster board cutout of the letter H. Scientists then moved their rig bit by bit, each time making more chirps, which bounced back the way they came, into the microphones. Using algorithms from seismic imaging, the system reconstructed a rough image of the letter H (above). The researchers also imaged a setup with the letters L and T and compared their acoustic results with an optical method. The optical method, which requires expensive equipment, failed to reproduce the more-distant L, and it took more than an hour, compared with just 4.5 minutes for the acoustic method. The researchers will present the work here Wednesday at the Computer Vision and Pattern Recognition conference. © 2019 American Association for the Advancement of Science

Keyword: Hearing
Link ID: 26333 - Posted: 06.18.2019

By Virginia Morell Most of us can look at two meal plates and easily tell which one has more food on it. But if someone turns out the lights, we’re out of luck. Not so for Asian elephants. A new study reveals that the pachyderms can judge food quantity merely by using their sense of smell, the first time an animal has been shown to do this. To conduct the research, scientists presented six Asian elephants (Elephas maximus) at an educational sanctuary in Thailand with two opaque, locked buckets containing 11 different ratios of sunflower seeds, a favorite treat. The elephants could not see how many seeds each bucket contained, but they could smell the contents through small holes in the lids. The animals chose the bucket with the greater quantity of food 59% to 82% of the time, the team reports today in the Proceedings of the National Academy of Sciences. (Even dogs, with their famed sense of smell, fail this test, other research has shown.) The discovery makes sense, the scientists say, because elephants are known to have the highest number of genes associated with olfactory reception of any species (about 2000 versus dogs’ 811). They can distinguish between the scent of Maasai pastoralists and Kamba farmers, and rely on their sense of smell to navigate long distances to find food and water (up to 19.2 kilometers). The researchers hope their findings could help mitigate human-elephant conflicts in Asia and Africa, because wandering herds use odors to decide where to travel; enticing scents might help lure them away from agricultural fields, for instance. © 2019 American Association for the Advancement of Science

Keyword: Chemical Senses (Smell & Taste)
Link ID: 26293 - Posted: 06.04.2019

Kerry Grens In mice whose sense of smell has been disabled, a squirt of stem cells into the nose can restore olfaction, researchers report today (May 30) in Stem Cell Reports. The introduced “globose basal cells,” which are precursors to smell-sensing neurons, engrafted in the nose, matured into nerve cells, and sent axons to the mice’s olfactory bulbs in the brain. “We were a bit surprised to find that cells could engraft fairly robustly with a simple nose drop delivery,” senior author Bradley Goldstein of the University of Miami Miller School of Medicine says in a press release. “To be potentially useful in humans, the main hurdle would be to identify a source of cells capable of engrafting, differentiating into olfactory neurons, and properly connecting to the olfactory bulbs of the brain. Further, one would need to define what clinical situations might be appropriate, rather than the animal model of acute olfactory injury.” Goldstein and others have independently tried stem cell therapies to restore olfaction in animals previously, but he and his coauthors note in their study that it’s been difficult to determine whether the regained function came from the transplant or from endogenous repair stimulated by the experimental injury to induce a loss of olfaction. So his team developed a mouse whose resident globose basal cells only made nonfunctional neurons, and any restoration of smell would be attributed to the introduced cells. © 1986–2019 The Scientist

Keyword: Chemical Senses (Smell & Taste); Stem Cells
Link ID: 26285 - Posted: 06.01.2019

Hannah Devlin Science correspondent A mind-controlled hearing aid that allows the wearer to focus on particular voices has been created by scientists, who say it could transform the ability of those with hearing impairments to cope with noisy environments. The device mimics the brain’s natural ability to single out and amplify one voice against background conversation. Until now, even the most advanced hearing aids work by boosting all voices at once, which can be experienced as a cacophony of sound for the wearer, especially in crowded environments. Nima Mesgarani, who led the latest advance at Columbia University in New York, said: “The brain area that processes sound is extraordinarily sensitive and powerful. It can amplify one voice over others, seemingly effortlessly, while today’s hearing aids still pale in comparison.” This can severely hinder a wearer’s ability to join in conversations, making busy social occasions particularly challenging. Scientists have been working for years to resolve this problem, known as the cocktail party effect. The brain-controlled hearing aid appears to have cracked the problem using a combination of artificial intelligence and sensors designed to monitor the listener’s brain activity. The hearing aid first uses an algorithm to automatically separate the voices of multiple speakers. It then compares these audio tracks to the brain activity of the listener. Previous work by Mesgarani’s lab found that it is possible to identify which person someone is paying attention to, as their brain activity tracks the sound waves of that voice most closely. © 2019 Guardian News & Media Limited

Keyword: Hearing
Link ID: 26247 - Posted: 05.18.2019

By Maggie Koerth-Baker Where is the loudest place in America? You might think New York City, or a major airport hub, or a concert you have suddenly become too old to appreciate. But that depends on what kind of noise you’re measuring. Sound is actually a physical thing. What we perceive as noise is the result of air molecules bumping into one another, like a Newton’s cradle toy. That movement eventually reaches our eardrums, which turn that tiny wiggle into an audible signal. But human ears can’t convert all molecular motion to sound. Sometimes the particles are jostling one another too fast. Sometimes they’re too slow. Sometimes, the motion is just happening in the wrong medium — through the Earth, say, instead of through the air. And when you start listening for the sounds we can’t hear, the loudest place in America can end up being right under your feet. Scientists have tools that can detect these “silent” waves, and they’ve found a lot of noise happening all over the U.S. Those noises are made by the cracking of rocks deep in the Earth along natural fault lines and the splashing of whitecaps on the ocean. But they’re also made by our factories, power plants, mines and military. “Any kind of mechanical process is going to generate energetic waves, said Omar Marcillo, staff scientist at Los Alamos National Laboratory. “Some of that goes through the atmosphere as acoustic waves, and some goes through the ground as seismic waves.” Marcillo’s work focuses on the seismic. © 2019 ABC News Internet Ventures.

Keyword: Hearing
Link ID: 26227 - Posted: 05.11.2019

By Heather Murphy The scent of lily of the valley cannot be easily bottled. For decades companies that make soap, lotions and perfumes have relied on a chemical called bourgeonal to imbue their products with the sweet smell of the little white flowers. A tiny drop can be extraordinarily intense. If you can smell it at all, that is. For a small percentage of people, it fails to register as anything. Similarly, the earthy compound 2-ethylfenchol, present in beets, is so powerful for some people that a small chunk of the root vegetable smells like a heap of dirt. For others, that same compound is as undetectable as the scent of bottled water. These — and dozens of other differences in scent perception — are detailed in a new study, published this week in the journal PNAS. The work provides new evidence of how extraordinarily different one person’s “smellscape” may be from another’s. It’s not that some people are generally better smellers, like someone else may have better eyesight, it’s that any one person might experience certain scents more intensely than their peers. “We’re all smelling things a little bit differently,” said Steven Munger, director of The Center for Smell and Taste at the University of Florida, who was not involved in the study. The scientists who conducted the study looked for patterns in subjects’ genetic code that could explain these olfactory differences. They were surprised to find that a single genetic mutation was linked to differences in perception of the lily of the valley scent, beet’s earthiness, the intensity of whiskey’s smokiness along with dozens of other scents. “I think it’s a very important finding,” said Stavros Lomvardas, a neuroscientist at Columbia University’s Zuckerman Institute, who was not involved in the research either. The study was conducted in a large room at Rockefeller University in New York City. Around 300 subjects were invited to sit in front of a computer screen surrounded by 150 jars of assorted odors. The screen alerted them to which jar sniff at any given time, and they then rated the intensity of each on a scale from 1 (extremely weak) to 7 (extremely strong) and pleasantness from 1 (extremely unpleasant) to 7 (extremely pleasant). © 2019 The New York Times Company

Keyword: Chemical Senses (Smell & Taste); Genes & Behavior
Link ID: 26203 - Posted: 05.03.2019

Nicola Davis Olfactory tests could help doctors spot older adults who are at greater risk of developing dementia, researchers say. The sense of smell is known to deteriorate with age. However, researchers have previously found it might also hint at health problems: older adults who struggle to identify odours have a greater chance of dying in the near future regardless of how old they are. Other studies have found older adults who have difficulties in identifying and remembering smells are more likely to have characteristics linked to a greater risk of developing Alzheimer’s disease even if there is no current sign of cognitive decline. Get Society Weekly: our newsletter for public service professionals Read more It is thought the sense of smell is one of the first faculties affected by certain neurodegenerative diseases. Now experts say they have probed further, and those diseases alone do not explain why a poor sense of smell might bode ill. “My suspicion is [the] process of smell in older adults probably has much broader potential health implications than what we already know about,” said Prof Honglei Chen, a co-author of the research from Michigan State University. He suggested it could be linked to conditions of the immune system and even psychiatric disorders. © 2019 Guardian News & Media Limited

Keyword: Alzheimers; Chemical Senses (Smell & Taste)
Link ID: 26184 - Posted: 04.30.2019

Lisa Wehrstedt Researchers in Philadelphia revealed last week that tastebuds also bear odour-detecting proteins, calling into question the idea that smell and taste come together in the brain to produce flavour. According to Dr Mehmet Hakan Ozdener, his findings open up the possibility of using smells to trick us into healthier eating, for example by adding a low-concentration odour to food to make it taste sweeter and thereby reduce sugar intake. It is believed that we all experience a form of motion-induced blindness while driving at night, when the red lights of the cars in front temporarily disappear if we move our eyes to the oncoming traffic. This phenomenon, where the brain ignores or discards visual information when it is placed in front of a moving background, was first observed in the lab in 1965. First described in 1976, the McGurk effect is a connection between hearing and vision in speech perception. When the auditory component of a syllable is paired with the visual component of another, this can lead to the perception of a third sound. Research conducted by the University of Oxford in 2013 suggests that the sight of cutlery and the perception of its size, weight, shape and colour have an effect on how we determine flavour, suggesting that the brain makes judgments on food even before it goes in our mouths. Yoghurt, for example, tastes sweeter on a white spoon than it does on a black spoon. © 2019 Guardian News & Media Limited

Keyword: Chemical Senses (Smell & Taste); Vision
Link ID: 26180 - Posted: 04.29.2019

By C. Claiborne Ray Q. Our dog escaped from the car. How did he find his way home the next day from nearly three miles away? A. What took so long? Dogs are well known for their ability to backtrack to a beloved home — or person. Most animal behavior experts attribute their navigating ability largely to a hypersensitive sense of smell. Three miles is not a great distance, compared with some of the epic homeward journeys that dogs have occasionally made, and a three-mile radius would be rich in odor guideposts. The theory is that a dog creates a map of scents from odiferous sites like a food store or fertilized garden — or even just a hint of an owner’s scent in the ground or air. Dogs are especially sensitive to the odor of the humans in their lives. One study used MRI imaging to study activity in the caudate nucleus, a brain area associated with the expectation of a reward. Dogs of varying breeds were exposed to their own scent or that of a familiar dog, a strange dog, a strange human or a familiar human. By far the strongest activation followed exposure to the scent of a familiar person. Another navigational clue may come from dogs’ suspected sensitivity to differences in magnetic orientation. A study of dozens of dogs found that they usually preferred to defecate with their bodies aligned in a north-south orientation, a preference that disappeared when the magnetic field was disturbed. © 2019 The New York Times Company

Keyword: Chemical Senses (Smell & Taste)
Link ID: 26144 - Posted: 04.16.2019

/ By Jed Gottlieb In 1983, The New York Times published a bombshell report about President Ronald Reagan: Starkey Laboratories had fitted the President, then 72, with a hearing aid. The news was welcomed by health professionals who reckoned it could help to reduce the stigma associated with hearing loss. At the time, one in three people over the age of 60 was thought to have hearing problems, though only around 20 percent who needed hearing aids used them. “The way I do the math, a third of all adults have unaddressed hearing issues. That’s lot of people.” Indeed, Reagan’s handlers knew too well that the revelation risked making the president look like a feeble old man — and worse, someone ill-equipped to run the most powerful nation on earth. “Among Presidential advisers,” The New York Times noted, “Mr. Reagan’s use of a hearing aid revived speculation on whether his age would be an issue if he seeks re-election next year.” Reagan won re-election, of course, but nearly 40 years later, negative perceptions persist — and health advocates are more concerned than ever. Hearing loss, they say, is not just a functional disability affecting a subset of aging adults. With population growth and a boom in the global elderly population, the World Health Organization (WHO) now estimates that by 2050, more than 900 million people will have disabling hearing loss. A 2018 study of 3,316 children aged nine to 11 meanwhile, found that 14 percent already had signs of hearing loss themselves. While not conclusive, the study linked the loss to the rise of portable music players. Copyright 2019 Undark

Keyword: Hearing
Link ID: 26124 - Posted: 04.09.2019

By Jamie Lauren Keiles When Jennifer Allen watched videos of space, she sometimes felt this peculiar sensation: a tingling that spread through her scalp as the camera pulled back to show the marble of the earth. It came in a wave, like a warm effervescence, making its way down the length of her spine and leaving behind a sense of gratitude and wholeness. Allen loved this feeling, but she didn’t know what caused it. It was totally distinct from anything she’d experienced before. Every two years or so she’d take to Google. She tried searching things like “tingling head and spine” or “brain orgasm.” For nine years, the search didn’t turn up anything. Then, around 2009, it did. As always, Allen typed her phrases into Google, but this time she got a result on a message board called SteadyHealth. The post was titled WEIRD SENSATION FEELS GOOD: i get this sensation sometimes. theres no real trigger for it. it just happens randomly. its been happening since i was a kid and i’m 21 now. some examples of what it seems has caused it to happen before are as a child while watching a puppet show and when i was being read a story to. as a teenager when a classmate did me a favor and when a friend drew on the palm of my hand with markers. sometimes it happens for no reason at all The poster went on to demand an explanation. In the discussion, nobody had one, but many described a similar feeling — a “silvery sparkle” inside the head, a euphoric “brain-gasm” or a feeling like goose bumps in the scalp that faded “in and out in waves of heightened intensity.” Many people agreed that the sensation was euphoric. (“Aside from an actual orgasm, it’s probably the most enjoyable sensation possible,” one user wrote.) Its triggers were as varied as watching someone fill out a form, listening to whispering sounds or seeing Bob Ross paint landscapes on TV. Allen scrolled through pages and pages of discussion. Oh my gosh, she remembers thinking. These people are talking about exactly what I experience. © 2019 The New York Times Company

Keyword: Pain & Touch; Hearing
Link ID: 26114 - Posted: 04.04.2019

Nell Greenfieldboyce Mosquitoes searching for a meal of blood use a variety of clues to track down humans, including our body heat and the carbon dioxide in our breath. Now, research shows that a certain olfactory receptor in their antennae also serves as a detector of humans, responding to smelly chemicals in our sweat. Targeting this receptor might offer a new way to foil blood-seeking mosquitoes and prevent the transmission of diseases including malaria, Zika virus and dengue, according to the study published Thursday in the journal Current Biology. "We found a receptor for human sweat, and we found that acidic volatiles that come off of us are really key for mosquitoes to find us," says Matthew DeGennaro, a neurogeneticist at Florida International University in Miami. "I think what's exciting about it is that finally we have evidence that there is some sort of pathway, in the sense of smell, that is required for mosquitoes to like us," says Lindy McBride, a scientist at Princeton University who studies mosquito behavior and was not part of the research team. It's long been known that mosquitoes rely on multiple clues to target humans. First, a mosquito will sense exhaled carbon dioxide from a distance that can be more than 30 feet. "After the carbon dioxide," DeGennaro explains, "then it begins to sense human odor." © 2019 npr

Keyword: Chemical Senses (Smell & Taste)
Link ID: 26092 - Posted: 03.29.2019

By James Gallagher Health and science correspondent, BBC News French scientists say they have proof that dogs can pick up the smell of an epileptic seizure. The University of Rennes team hope the findings could lead to ways to predict when people will have a seizure. These could include dogs or "electronic noses" that pick up the precise odour being given off during a seizure. Dogs have previously been shown to be able to sniff out diseases including cancers, Parkinson's, malaria and diabetes. Some people with epilepsy already rely on the animals. One sleeping in a child's bedroom can alert family members of a seizure in the middle of the night. The latest study, in the journal Scientific Reports, trained five dogs from Medical Mutts, in the US, to recognise the smell of sweat taken from a patient having a seizure. They were then given a choice of seven sweat samples taken from other patients while they were either relaxing, exercising or having a seizure. Two of the dogs found the seizure sample about two-thirds of the time and the other three were 100% accurate The report says: "The results are extremely clear and constitute a first step towards identifying a seizure-specific odour." © 2019 BBC

Keyword: Chemical Senses (Smell & Taste); Epilepsy
Link ID: 26091 - Posted: 03.29.2019

By Richard Klasco, M.D. Q. I have completely lost my sense of smell and can taste only a few things. I have seen doctors and taken tests, but no answers. I know I’m not the only one with this problem. Any ideas? A. Humans are able to perceive an astounding one trillion odors. But our sense of smell is fragile. About a quarter of adults, and more than half of those over 80, have some degree of olfactory impairment. The sense of taste is often affected at the same time, as the neural pathways of smell and taste commingle in the brain. Having an impaired sense of smell may be more than a nuisance. Studies have linked a decreased sense of smell to a heightened risk for Parkinson’s disease, Alzheimer’s disease, multiple sclerosis and premature death. Common causes of a decreased sense of smell include nasal problems, such as deviated septum and nasal polyps; viruses, such as rhinovirus and Epstein-Barr virus; chronic sinusitis; head injury; and certain cancers. Environmental exposure to cigarette smoke, alcohol, air pollution and toxins further increase the risk. Yet, in about 16 percent of people, no cause can be identified. Eating nuts and fish has been associated with protection against smell impairment, as have exercise and use of cholesterol-lowering drugs and oral steroids. It is unknown, however, whether changing one’s dietary or exercise habits will improve the sense of smell. Medical evaluation typically begins with an otolaryngologist, an ear, nose and throat doctor who will use a standardized scratch-and-sniff test to assess any olfactory deficits. Laboratory tests of blood and nasal mucus and imaging studies, such as CT or M.R.I. scans, are often needed. In some cases, endoscopic surgery, a flexible camera inserted into the nose, may aid in diagnosis and provide therapeutic benefits. © 2019 The New York Times Company

Keyword: Chemical Senses (Smell & Taste)
Link ID: 26062 - Posted: 03.22.2019

Ian Sample Science editor Scientists have developed a test for Parkinson’s disease based on its signature odour after teaming up with a woman who can smell the condition before tremors and other clinical symptoms appear. The test could help doctors diagnose patients sooner and identify those in the earliest stages of the disease, who could benefit from experimental drugs that aim to protect brain cells from being killed off. Perdita Barran, of the University of Manchester, said the test had the potential to decrease the time it took to distinguish people with normal brain ageing from those with the first signs of the disorder. “Being able to say categorically, and early on, that a person has Parkinson’s disease would be very useful,” she said. Get Society Weekly: our newsletter for public service professionals Read more Most people cannot detect the scent of Parkinson’s, but some who have a heightened sense of smell report a distinctive, musky odour on patients. One such “super smeller” is Joy Milne, a former nurse, who first noticed the smell on her husband, Les, 12 years before he was diagnosed. Milne only realised she could sniff out Parkinson’s when she attended a patient support group with her husband and found everyone in the room smelled the same. She thought little more about it until she mentioned the odour to Tilo Kunath, a neurobiologist who studies Parkinson’s at Edinburgh University. © 2019 Guardian News & Media Limited

Keyword: Parkinsons; Chemical Senses (Smell & Taste)
Link ID: 26056 - Posted: 03.20.2019

Maria Temming A new analysis of people’s brain waves when surrounded by different magnetic fields suggests that people have a “sixth sense” for magnetism. Birds, fish and some other creatures can sense Earth’s magnetic field and use it for navigation (SN: 6/14/14, p. 10). Scientists have long wondered whether humans, too, boast this kind of magnetoreception. Now, by exposing people to an Earth-strength magnetic field pointed in different directions in the lab, researchers from the United States and Japan have discovered distinct brain wave patterns that occur in response to rotating the field in a certain way. These findings, reported in a study published online March 18 in eNeuro, offer evidence that people do subconsciously respond to Earth’s magnetic field — although it’s not yet clear exactly why or how our brains use this information. “The first impression when I read the [study] was like, ‘Wow, I cannot believe it!’” says Can Xie, a biophysicist at Peking University in Beijing. Previous tests of human magnetoreception have yielded inconclusive results. This new evidence “is one step forward for the magnetoreception field and probably a big step for the human magnetic sense,” he says. “I do hope we can see replications and further investigations in the near future.” During the experiment, 26 participants each sat with their eyes closed in a dark, quiet chamber lined with electrical coils. These coils manipulated the magnetic field inside the chamber such that it remained the same strength as Earth’s natural field but could be pointed in any direction. Participants wore an EEG cap that recorded the electrical activity of their brains while the surrounding magnetic field rotated in various directions. |© Society for Science & the Public 2000 - 2019

Keyword: Pain & Touch
Link ID: 26052 - Posted: 03.19.2019