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By Michelle Roberts Health reporter, BBC News Scientists believe they have discovered the genetic code that makes some people sleepwalk. By studying four generations of a family of sleepwalkers they traced the fault to a section of chromosome 20. Carrying even one copy of the defective DNA is enough to cause sleepwalking, the experts told the journal Neurology. They hope to target the genes involved and find new treatments for the condition that affects up to 10% of children and one in 50 adults. Most often, sleepwalking is a fairly benign problem and something that will be outgrown. Many children will have episodes where they will arise from their sleep in a trance-like state and wander. But more extreme cases of sleepwalking can be deeply disruptive and downright dangerous, particularly when the condition persists into adulthood. Sleepwalkers may perform complex feats such as locating the car keys, unlocking the doors and then driving. There have even been high-profile cases where sleepwalkers have killed during an episode. BBC © MMXI
Keyword: Sleep; Genes & Behavior
Link ID: 14969 - Posted: 02.08.2011
Eating chips, chocolate and cake may be damaging to a child's intelligence, according to researchers at Bristol University. Their study suggests a link between a diet high in processed foods and a slightly lower IQ. Writing in the Journal of Epidemiology and Community Health, they suggest poor nutrition may affect brain development. The British Dietetic Association said more young parents needed to be educated about healthy eating. The eating habits of 3,966 children taking part in the The Avon Longitudinal Study of Parents and Children were recorded at the ages of three, four, seven and eight and a half. The researchers said three types of diet emerged: Processed diets which were high in fat, sugar and convenience foods, traditional diets of meat, potato and vegetables, and health conscious diets of salads, fruit and fish. The children all took IQ tests when they were eight and half. The researchers found a link between IQ and diet, even after taking into account other factors such as the mother's level of education, social class and duration of breast feeding. BBC © MMXI
Keyword: Development of the Brain; Intelligence
Link ID: 14968 - Posted: 02.08.2011
Human brains have shrunk over the past 30,000 years, puzzling scientists who argue it is not a sign we are growing dumber but that evolution is making the key motor leaner and more efficient. The average size of modern humans -- Homo sapiens -- has decreased about 10 percent during that period -- from 1,500 to 1,359 cubic centimeters (91 to 83 cubic inches), the size of a tennis ball. Women's brains, which are smaller on average than those of men, have experienced an equivalent drop in size. These measurements were taken using skulls found in Europe, the Middle East and Asia. "I'd called that a major downsizing in an evolutionary eye blink," John Hawks of the University of Michigan told Discover magazine. But other anthropologists note that brain shrinkage is not very surprising since the stronger and larger we are, the more gray matter we need to control this larger mass. The Neanderthal, a cousin of the modern human who disappeared about 30 millennia ago for still unknown reasons, was far more massive and had a larger brain. The Cro-Magnons who left cave paintings of large animals in the monumental Lascaux cave over 17,000 years ago were the Homo sapiens with the biggest brain. They were also stronger than their modern descendants. Psychology professor David Geary of the University of Missouri said these traits were necessary to survive in a hostile environment. He has studied the evolution of skull sizes 1.9 million to 10,000 years old as our ancestors and cousins lived in an increasingly complex social environment. © 2011 Discovery Communications, LLC.
Keyword: Evolution; Intelligence
Link ID: 14967 - Posted: 02.08.2011
by Douglas Fox A STRANGE contraption, a cross between a deli meat slicer and a reel-to-reel film projector, sits in a windowless room in Cambridge, Massachusetts. It whirs along unsupervised for days at a time, only visited occasionally by Narayanan Kasthuri, a mop-haired postdoc at Harvard University, who examines the strip of film spewing out. It may seem unlikely, but what's going on here may revolutionise neuroscience. Spaced every centimetre along the film are tiny dots, each of which is a slice of mouse brain, one-thousandth the thickness of a sheet of aluminium foil. This particular roll of film contains 6000 slices, representing a speck of brain the size of a grain of salt. The slices of brain will be turned into digital images by an automated electron microscope. A computer will read those images, trace the outlines of nerve cells, and stack the pictures into a 3D reconstruction. In the jargon, they are building the mouse "connectome", named in line with the term "genome" for the sequence of all of an organism's genes, "proteome" for all its proteins, and so on. It's an epic undertaking. The full mouse connectome would produce hundreds of times more data than can be found on all of Google's computers, says Jeffrey Lichtman, the neuroanatomist leading the Harvard team. And yet it's just the beginning. Their efforts could be seen as a dry run for a project that is at least four orders of magnitude greater: mapping the human connectome. © Copyright Reed Business Information Ltd.
Keyword: Development of the Brain
Link ID: 14966 - Posted: 02.08.2011
Researchers believed neurons in the brain communicated through physical connections known as synapses. However, EU-funded neuroscientists have uncovered strong evidence that neurons also communicate with each other through weak electric fields, a finding that could help us understand how biophysics gives rise to cognition. The study, published in the journal Nature Neuroscience, was funded in part by the EUSYNAPSE ('From molecules to networks: understanding synaptic physiology and pathology in the brain through mouse models') project, which received EUR 8 million under the 'Life sciences, genomics and biotechnology for health' Thematic area of the EU's Sixth Framework Programme (FP6). Lead author Dr Costas Anastassiou, a postdoctoral scholar at the Californian Institute of Technology (Caltech) in the US, and his colleagues explain how the brain is an intricate network of individual nerve cells, or neurons, that use electrical and chemical signals to communicate with one another. Every time an electrical impulse races down the branch of a neuron, a tiny electric field surrounds that cell. A few neurons are like individuals talking to each other and having small conversations. But when they all fire together, it's like the roar of a crowd at a sports game. That 'roar' is the summation of all the tiny electric fields created by organised neural activity in the brain. While it has long been recognised that the brain generates weak electrical fields in addition to the electrical activity of firing nerve cells, these fields were considered epiphenomenon - superfluous side effects.
Keyword: Miscellaneous
Link ID: 14965 - Posted: 02.08.2011
By EMILY BAZELON At 4 months, Noah Whitmer was an easy baby. Super tranquilo, remembers Trudy Eliana Muñoz Rueda, who took care of Noah at her home day care center in Fairfax County, Va. Rueda and Noah’s mother, Erin Whitmer, both noticed when he stopped taking his bottle well and napping as usual in the middle of his fifth month, in April 2009. Whitmer thought this was because Noah had just started eating solid food. She and Rueda talked about it early on April 20, both of them hunched over Noah in his car seat when Whitmer dropped him off. That afternoon, after a morning in which Noah didn’t nap and drank only a couple of ounces of formula, Rueda says she prepared a bottle for him while he lay on a mat. In her native Peru, Rueda, who is 46, ran a travel agency and taught college courses for prospective tour guides. Her husband was trained as a lawyer. After they moved to the United States in 2001, the couple had a second child, and three years later Rueda converted her basement into a home day care center so she could work while spending time with her two kids. When Rueda sat down to feed Noah, her 13-year-old daughter was at school, her 5-year-old was upstairs watching TV and the four other children in her care were taking naps. Rueda’s sister-in-law, who spent the morning with the children while Rueda was at a doctor’s appointment, had just left the house. “Everything was calm and quiet,” Rueda, who has soft features and dark hair, told me in Spanish while her lawyer translated. There are two irreconcilable versions of how that calm shattered. Rueda says that Noah was crying, and she picked him up, sat on the couch and gave him the bottle to help put him to sleep. While she was feeding him, she felt Noah’s arm go limp, and when she moved to take the bottle out of his mouth, he made a sound that she didn’t recognize. “I could tell something was happening,” she says. She stood up and put Noah on her shoulder, patting him on the back. “As I did this, his body tensed up in a ball. It was as if he was looking for air, and he couldn’t breathe.” © 2011 The New York Times Company
Keyword: Brain Injury/Concussion; Development of the Brain
Link ID: 14964 - Posted: 02.07.2011
A tiny, translucent water flea that can reproduce without sex and lives in ponds and lakes has more genes than any other creature, said scientists who have sequenced the crustacean's genome. Daphnia pulex, named after the nymph in Greek mythology who transforms into a tree in order to escape the lovestruck Apollo, has 31,000 genes compared to humans who have about 23,000, said the research in the journal Science. Often studied by scientists who want to learn about the effects of pollution and environmental changes on water creatures, the almost-microscopic freshwater Daphnia is the first crustacean to have its genome sequenced. But just because this creature -- viewed as the canary in the gold mine of the world's waters -- has more genes doesn't necessarily mean they are all unique, explained project leader John Colbourne. "Daphnia's high gene number is largely because its genes are multiplying, by creating copies at a higher rate than other species," said Colbourne, genomics director at the Center for Genomics and Bioinformatics. Daphnia has a large number of never-before seen genes, as well as a big chunk of the same genes found in humans, the most of any insects or crustacean so far known to scientists. "More than one-third of Daphnia's genes are undocumented in any other organism -- in other words, they are completely new to science," said Don Gilbert, coauthor and Department of Biology scientist at IU Bloomington. © 2011 Discovery Communications, LLC.
Keyword: Genes & Behavior
Link ID: 14963 - Posted: 02.07.2011
MICHAEL POSNER Among the great enigmas of human existence, few have proven so intractable as the human brain. Neuroscientist V.S. Ramachandran says our current understanding of the body’s most complex organ approximates what we knew about chemistry in the 19th century: in short, not much. On a scale of 100, estimates Toronto psychiatrist Colin Shapiro, our comprehension of how the brain actually functions ranks at a lowly 2. Now, two Toronto doctors, a general practitioner and a medical biophysicist, are laying claim to a research innovation that could expand our knowledge exponentially. Using one of the earliest imaging technologies, the electroencephalograph (EEG), Mark Doidge and Joseph Mocanu have written software that creates dynamic, real-time, three-dimensional colour movies of the brain. If their research is validated, it could revolutionize neuroscience – and, not incidentally, make them a fortune. But while the software is proven, its application to medical treatment has yet to be clinically tested in traditional, double-blind studies. “We usually think of cameras as looking out at the world,” Dr. Doidge said. “This is a new kind of camera. It gives you a window on your mind.” It’s not a camera in the conventional sense. Instead, adapting an algorithm known as eLORETA, the software amplifies EEG signals from 32 electrodes attached to the cerebral cortex, and converts them into colour-coded movies of neuronal activity. In a brain divided in more than 6,200 voxels (3D pixels), the algorithm infers and maps where electrical events are occurring. The movie can then be watched in real time, recorded and played back on computer screens. © Copyright 2011 The Globe and Mail Inc.
Keyword: Brain imaging
Link ID: 14962 - Posted: 02.07.2011
By James Gallagher Health reporter, BBC News An international team of researchers have found a clue to one of the leading causes of blindness, which they hope could eventually lead to a cure. Age-related macular degeneration affects 500,000 people in the UK and is incurable. The study in the journal Nature found an enzyme known as DICER1 that stops functioning, resulting in the illness. UK experts said it had the potential to be an important breakthrough. The macula is a part of the eye which sits in the centre of the retina and is responsible for the fine detail at the centre of the field of vision. As the disease progresses that central vision declines, making reading, driving and recognising people difficult. It affects one in 50 people over 50 and one in five people over 85. The exact cause is unknown, but risk factors include smoking, high blood pressure and having relatives with the condition. BBC © MMXI
Keyword: Vision
Link ID: 14961 - Posted: 02.07.2011
Joseph Milton Fly brains have never looked so good. Spectacular images of the insects' complex neural circuitry have now been produced using a pair of techniques that allow individual nerve-cell lineages to be visualized using a range of colours. Both methods are adaptations of the 'Brainbow' techniques devised at Harvard University in Cambridge, Massachusetts, to visualize mouse neurons, and reported in Nature in 20071. "We were inspired by the elegance of the Brainbow approach," says Iris Salecker, a neuroscientist at the National Institute for Medical Research in London, who worked on one of the fruitfly methods. The new techniques, reported in two papers published online today in Nature Methods23, involve inserting strings of genes into the neurons of Drosophila melanogaster embryos. Each gene produces a different fluorescent colour, lighting up individual neurons, or even all of the cells descended from an embryonic neuron - because they will carry the same gene and therefore be the same colour. Both techniques result in colourful visualizations that allow all the nerve cells in any one lineage to be distinguished and their development traced, illuminating how neural circuits develop and interact. The string includes a selection of colour-producing genes, but only one gene is active in each modified nerve cell — the one closest to a region of DNA called a promoter. As the strings are identical, all the modified neurons would be the same colour, and would be impossible to separate visually. © 2011 Nature Publishing Group,
Keyword: Brain imaging; Genes & Behavior
Link ID: 14960 - Posted: 02.07.2011
A Devon man suffering from Tourette's Syndrome is to undergo a pioneering form of brain surgery. Mike Sullivan, 32, from Exeter, will have deep brain stimulation to help reduce his involuntary tics. It sends electrical impulses to control brain activity and has proved effective in treating Parkinson's disease, cluster headaches and depression. Tourette's is a neurological disorder thought to occur if there is a problem with nerves communicating in the brain. People suffering from Tourette's usually have both motor and vocal tics. Mr Sullivan, who was diagnosed with the condition at the age of 12, became the victim of bullying and teasing at school. He opted for deep brain stimulation after his condition worsened and symptoms became more frequent. Mr Sullivan said he has to work hard to suppress the almost continual tics while working with the public at Exeter Register Office. He describes this experience as exhausting and mentally draining. "I can, up to a point, control it... but I'm always looking for a way out if people are staring," he told BBC News. BBC © MMXI
Keyword: Tourettes
Link ID: 14959 - Posted: 02.07.2011
NEW YORK (Reuters Health) - More than a quarter of Americans taking antidepressants have never been diagnosed with any of the conditions the drugs are typically used to treat, according to new research. That means millions could be exposed to side effects from the medicines without proven health benefits, researchers say. "We cannot be sure that the risks and side effects of antidepressants are worth the benefit of taking them for people who do not meet criteria for major depression," said Jina Pagura, a psychologist and currently a medical student at the University of Manitoba in Canada, who worked on the study. "These individuals are likely approaching their physicians with concerns that may be related to depression, and could include symptoms like trouble sleeping, poor mood, difficulties in relationships, etc.," she added in an e-mail to Reuters Health. "Although an antidepressant might help with these issues, the problems may also go away on their own with time, or might be more amenable to counseling or psychotherapy." The researchers tapped into data from the Collaborative Psychiatric Epidemiologic Surveys, which include a nationally representative sample of more than 20,000 U.S. adults interviewed between 2001 and 2003. Roughly one in ten people told interviewers they had been taking antidepressants during the past year. Yet a quarter of those people had never been diagnosed with any of the conditions that doctors usually treat with the medication, such as major depression and anxiety disorder. SOURCE: http://bit.ly/eXPVSL Journal of Clinical Psychiatry, online January 25, 2011. Copyright 2011 Thomson Reuters.
Keyword: Depression
Link ID: 14958 - Posted: 02.05.2011
By BINA VENKATARAMAN BOSTON — Tracking the inexorable advance of amyotrophic lateral sclerosis, the deadly neuromuscular ailment better known as Lou Gehrig’s disease or A.L.S., has long been an inexact science — a matter of monitoring weakness and fatigue, making crude measurements of the strength of various muscles. This imprecision has hindered the search for drugs that could slow or block the disease’s progress. But now a neurologist at Beth Israel Deaconess Medical Center here has won a $1 million prize — reportedly the largest ever for meeting a specific challenge in medical research — for developing a reliable way to quantify the small muscular changes that signal progressive deterioration. The winner, Dr. Seward Rutkove, showed that his method could cut in half the cost of clinical trials to screen potential drugs for the disease, said Melanie Leitner, chief scientific officer of Prize4Life, the nonprofit group that created the competition. The method does not provide a target in the body at which to aim drugs, nor will it help doctors better diagnose the disease. But Dr. Merit Cudkowicz, a professor of neurology at Massachusetts General Hospital and a chairwoman of the Northeast A.L.S. Consortium, compared Dr. Rutkove’s discovery to the way magnetic resonance imaging expedited the development of drugs for multiple sclerosis. “You can use this as a tool to screen drugs to see if they will affect survival,” she said, but added, “The ultimate prize is finding a drug that works for A.L.S.” © 2011 The New York Times Company
Keyword: ALS-Lou Gehrig's Disease
Link ID: 14957 - Posted: 02.05.2011
by Valerie Ross Jesse Rissman cannot read your mind—but he’s working on it. A postdoctoral memory researcher at Stanford University, Rissman is studying how much fMRI scans (which measure activity in the brain) can reveal about what a person is thinking. Along the way, he is raising a big red flag to those who want to use brain scans to peer into the heads of suspected criminals. What got you interested in brain scans in the courtroom? In India, a woman was convicted of murder using a technology that recorded electrical activity from the scalp while she was viewing or listening to materials related to the crime. When I learned more about the tests and how widely they were being used in the Indian legal system, I realized these techniques need to be evaluated in a more rigorous way. How do you look for memories? We had people study photographs of faces. Then, while they were in an fMRI scanner, we showed them those faces again, interspersed with new ones, and they had to judge whether they recognized each face. Then we used a computer algorithm to identify neural signatures associated with recognition and those associated with the experience of something new. Can you identify a person’s memories from such scans? We could tell quite reliably whether people thought each face was familiar or new, but we couldn’t tell the true status of the memory. When we tried to distinguish faces the person had seen from those he hadn’t, we were correct less than 60 percent of the time. There are many reasons memories may not properly form. The person may not be paying attention, may be under the influence of a substance, may be drowsy—and memories are forgotten over time. The idea that our brain contains a veridical record of our experiences is, I think, fanciful. Copyright © 2011, Kalmbach Publishing Co.
Keyword: Brain imaging
Link ID: 14956 - Posted: 02.05.2011
Catherine de Lange, reporter Did this video mess with your mind? If you're wondering whether it's a camera trick, print off your own template of the illusion and try it yourself. It's an old trick devised by American psychologist Joseph Jastrow. Although both of the shapes are the same size, the one on the bottom looks bigger. The brain trick is thought to occur because the short edge of one shape is lined up against the longer side of the other. However, there is still no consensus among researchers on why our brains perceive this effect. The illusion was recreated here by psychologist Richard Wiseman, who will be revealing why our brain is hard-wired for weirdness in his new book, Paranormality, coming out next month. Last week's illusion We asked you for possible explanations for an illusion in which a ring of bubbles appeared to shift upwards as they changed from light to dark. We found a number of possible explanations for the effect, so we asked Arthur Shapiro from the American University of Washington, in Washington DC, who has conducted experiments with similar illusions, to help us out. He thought the illusion was delightful since it combines two different effects. One of these has to do with how our brains perceive light emitted from a surface. "The eye sends information to the brain based on the contrast between lights, not on the information at a single pixel itself," says Shapiro. When brightness suddenly changes at the edge of a shape, our brains perceive it as motion. This effect was first observed by psychologists Richard Gregory and Priscilla Heard in 1983. © Copyright Reed Business Information Ltd.
Keyword: Vision
Link ID: 14955 - Posted: 02.05.2011
By MICHELLE ANDREWS MAYBE the question is not who suffers from some type of chronic pain, but who doesn’t? “If you tally up everybody who has chronic, recurring back, headache and musculoskeletal problems, it includes almost everybody by the time people get into their 30s,” said Dr. Perry Fine, a professor of anesthesiology at the Pain Research Center and the University of Utah and incoming chairman of the American Academy of Pain Medicine. Given the prevalence of chronic pain — often defined as recurrent pain that lasts more than three to six months — you might expect that by now medical science would have figured out how to alleviate it and that health insurers would routinely cover its treatment. If only it were that simple. Pain is a sneaky opponent. Invisible, it cannot be detected with a blood test or a scan; sometimes it has no identifiable cause. Pain is perception, and what one person considers intolerable may be only moderately uncomfortable to another. This makes treatment challenging. And insurers often do not make it any easier. For the last 15 years, Ernie Merritt III, 46, has been coping with the aftermath of a back injury he suffered working as a pipefitter in southeastern Maine. At the time, he thought he had just pulled a muscle. But after an M.R.I. revealed a herniated disc pressing on his sciatic nerve, he underwent the first of four operations. © 2011 The New York Times Company
Keyword: Pain & Touch
Link ID: 14954 - Posted: 02.05.2011
By DWIGHT GARNER Judith Guest’s 1976 novel, “Ordinary People,” and the 1980 film adaptation starring Timothy Hutton, were groundbreaking because they underscored Ms. Guest’s title. Mental illness could occur in the most ordinary families, these works suggested. It could happen to anyone. The appeal of the Irish journalist Patrick Cockburn’s distressing new memoir, written with his son Henry, is quite the opposite, because the large Cockburn family is completely extraordinary. “Henry’s Demons” is about how Henry Cockburn, in 2002, at the age of 20, received a diagnosis of schizophrenia. He was enrolled at the University of Brighton at the time. Trees began talking to him; he leapt naked into frozen lakes; he soiled his pants on a regular basis; he ate raw garlic; his hair became matted into a single mephitic dreadlock; he roamed the woods, his crotch becoming infested with insects; he began to resemble Jesus or a caveman. He would be in and out of mental institutions, all across England, for nearly the next decade. The charming young man his family had known was largely gone. This is an awful, hard-to-witness, downbound train of a story. The book’s last sentence, written by Henry, is as startling as the moment in a horror movie when the mutilated monster, long presumed dead, flicks opens its green eyes. © 2011 The New York Times Company
Keyword: Schizophrenia
Link ID: 14953 - Posted: 02.05.2011
By Jennifer Viegas In socially monogamous species, from birds to humans, most individuals find partners. A large proportion of females, however, wind up with unattractive males of below-average quality, according to a new study that also found such less-than-ideal relationships raise female stress levels. The findings negate prior theories that, in monogamous species throughout the animal kingdom, each female has a good chance of pairing with a male that matches her ideal choice of partner. "In socially monogamous animals, very few individuals end up with the perfect partner because, of course, he or she is likely to be paired to someone else. That is, lots of men would like to be married to, say, Angelina Jolie, and lots of women would love to be married to Brad Pitt. But the reality is that they can't and only someone like Brad Pitt is able to marry someone like Angelina Jolie," lead author Simon Griffith told Discovery News. "So how does a female respond to her real partner?" Griffith, an associate professor in Macquarie University's Department of Biological Sciences, asked. "Work over the past few decades has shown that females can actually make a number of subtle strategies to improve their own fitness," he added, explaining that these include sleeping with other males that could improve the genetic fitness of any potential offspring. To determine what might underlie such behavior, Griffith and colleagues Sarah Pryke and William Buttemer observed partnerships and mating in Gouldian finches. © 2011 Discovery Communications, LLC.
Keyword: Sexual Behavior
Link ID: 14952 - Posted: 02.03.2011
By Jennifer Viegas When a Southpaw shakes hands, his left eye and the right portion of his brain are working hard to process the other individual, suggests a new study. The research helps to explain why hand and limb preferences exist across numerous species. The predisposition, as it turns out, are tied to ocular dominance, or the tendency to prefer visual input from one eye over the other, according to the study, published in the latest Royal Society Biology Letters. Ocular dominance, in turn, is driven by cerebral lateralization, which refers to how information processing is divided and coordinated between the brain's left and right hemispheres. In recent U.S. history, the majority of presidents have been left-handed (Gerald Ford, Ronald Reagan, George H.W. Bush, William Clinton and Barack Obama), but scientists haven't yet found a link between hand preference and an individual's abilities. "At this stage we have no reason to think that left- or right-brained animals are superior or analyze information differently, except that it's the mirror image," co-author Culum Brown told Discovery News. Brown, director of Advanced Biology at Macquarie University, and colleague Maria Magat studied the phenomenon in Australian parrots. These birds, like humans, have a tendency to use either their right or left limb more than the other. © 2011 Discovery Communications, LLC. T
Keyword: Laterality; Vision
Link ID: 14951 - Posted: 02.03.2011
by Ferris Jabr While we doze, our brain busily squirrels away memories. But not just any memories – it turns out that during sleep the brain specifically preserves nuggets of thought it previously tagged as important. Jan Born of the University of Tübingen in Germany and his colleagues asked 191 adults to perform different memory tasks, such as learning word-pairs. Half were told to expect a test on the task 9 hours later, while the others were told they would have a different kind of task. During the interval some members of each group were allowed to sleep. Participants who went to bed anticipating a post-nap quiz recalled 12 per cent more word pairs than those who slept with no expectation of a test. Furthermore, those anticipating a test also experienced more slow-wave sleep, known to be linked to memory consolidation. By itself sleep did not significantly improve memory – participants who were not anticipating a test performed just as badly as one another regardless of whether or not they'd had a nap before the exam. The results improve our understanding of sleep, says Born. "There is an active memory process during sleep that selects certain memories and puts them in long-term storage." Journal reference: Journal of Neuroscience, DOI: 10.1523/jneurosci.3575-10.2011 Issue 2798 of New Scientist magazine © Copyright Reed Business Information Ltd.
Keyword: Sleep; Learning & Memory
Link ID: 14950 - Posted: 02.03.2011


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